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Name Notes Model

Molecule Parameter List for CaM_Ca_n_dash_CaNAB

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network. The text color of a molecule is highlighted by color.

Statistics

CaM_Ca_n_dash_CaNAB participated as	Molecule	Sum total of	Enzyme	Substrate of an enzyme	Product of an enzyme	Substrate in Reaction	Product in Reaction
No. of occurrences	1	1	3	0	0	0	0

Accession and Pathway Details

Accession Name	Accession No.	Accession Type	Pathway Link
Differential syn thesis of mRNA	95	Network	kinetics,  compartment_1,  compartment_2
The model consists of three major pathways: Calcium-calmodulin dependent protein kinase IV (CaMKIV), Mitogen-activated protein kinase (MAPK) and Protein Phosphatase 1 (PP1). Each of these converged on CREB activation. We also modeled further interactions with Transducer of regulated CREB activity 1 (TORC1) and the protein kinase A (PKA) pathway.

CaM_Ca_n_dash_CaNAB acting as a Molecule in  Differential synthesis of mRNA Network

Name	Accession Name	Pathway Name	Initial Conc. (uM)	Volume (fL)	Buffered
CaM_Ca_n_dash_CaNAB	Differential syn thesis of mRNA Accession No. : 95	kinetics Pathway No. : 1115	0	1000	No

CaM_Ca_n_dash_CaNAB acting as a Summed Molecule in  Differential synthesis of mRNA Network

Accession Name	Pathway Name	Target	Input
Differential syn thesis of mRNA Accession No. : 95	kinetics Pathway No. : 1115	CaM_Ca_n_dash_CaNAB	CaMCa4_dash_ CaNAB CaMCa3_dash_ CaNAB CaMCa2_dash_ CANAB

CaM_Ca_n_dash_CaNAB acting as an Enzyme in  Differential synthesis of mRNA Network

	Enzyme Molecule / Enzyme Activity	Accession Name	Pathway Name	Km (uM)	kcat (s^-1)	Ratio	Enzyme Type	Reagents
1	CaM_Ca_n_dash_ CaNAB / dephosph_inhib1	Differential syn thesis of mRNA Accession No. : 95	kinetics Pathway No. : 1115	4.9708	0.34	4	explicit E-S complex	Substrate I1_star Product I1
2	CaM_Ca_n_dash_ CaNAB / CaN_dephos_ TORC1	Differential syn thesis of mRNA Accession No. : 95	kinetics Pathway No. : 1115	0.4	0.1	4	explicit E-S complex	Substrate pTORC1 Product TORC1c
3	CaM_Ca_n_dash_ CaNAB / dephosph_dash_ PP1_dash_I_star	Differential syn thesis of mRNA Accession No. : 95	kinetics Pathway No. : 1115	4.9708	0.34	4	explicit E-S complex	Substrate PP1_dash_I1_ star Product PP1_dash_I1