DOQCS database

NCBS Home page

Accession List

Pathway List

Authorized Users

Help

News archives

Enter a Search String

Special character and space not allowed in the query term. Search string should be at least 2 characters long.

Molecule Parameter List for Nucleotides

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by

color.

Statistics

*Nucleotides* participated as	Molecule	Sum total of	Enzyme	Substrate of an enzyme	Product of an enzyme	Substrate in Reaction	Product in Reaction
No. of occurrences	1	0	0	6	0	0	0

Accession and Pathway Details

Accession Name	Accession No.	Accession Type	Pathway Link
Differential syn thesis of mRNA	95	Network	kinetics, compartment_1, compartment_2
The model consists of three major pathways: Calcium-calmodulin dependent protein kinase IV (CaMKIV), Mitogen-activated protein kinase (MAPK) and Protein Phosphatase 1 (PP1). Each of these converged on CREB activation. We also modeled further interactions with Transducer of regulated CREB activity 1 (TORC1) and the protein kinase A (PKA) pathway.

Nucleotides acting as a Molecule in Differential synthesis of mRNA Network

Name	Accession Name	Pathway Name	Initial Conc. (uM)	Volume (fL)	Buffered
Nucleotides	Differential syn thesis of mRNA Accession No. : 95	compartment_1 Pathway No. : 1116	0.2	370	Yes

Nucleotides acting as a Substrate for an Enzyme in Differential synthesis of mRNA Network

	Enzyme Molecule / Enzyme Activity	Accession Name	Pathway Name	Km (uM)	kcat (s^-1)	Ratio	Enzyme Type	Reagents
1	Basal_ transcription / basal_mRNA_ synthesis	Differential syn thesis of mRNA Accession No. : 95	compartment_1 Pathway No. : 1116	1.0812	0.05	4	explicit E-S complex	Substrate Nucleotides Product mRNA_clx

2	Basal_ transcription / basal_CaMKIV	Differential syn thesis of mRNA Accession No. : 95	compartment_1 Pathway No. : 1116	1.08	0.05	4	explicit E-S complex	Substrate Nucleotides Product mRNA_clx_CaMKIV

3	Basal_ transcription / basal_PP1mRNA	Differential syn thesis of mRNA Accession No. : 95	compartment_1 Pathway No. : 1116	1.08	0.05	4	explicit E-S complex	Substrate Nucleotides Product PP1mRNA_clx

4	Transcription_ clx / mRNA_syn	Differential syn thesis of mRNA Accession No. : 95	compartment_1 Pathway No. : 1116	1.08	0.05	4	explicit E-S complex	Substrate Nucleotides Product mRNA_clx

5	Transcription_ Clx_C / mRNA_CaMKIV	Differential syn thesis of mRNA Accession No. : 95	compartment_1 Pathway No. : 1116	1.08	0.05	4	explicit E-S complex	Substrate Nucleotides Product mRNA_clx_CaMKIV

6	Transcr_clx_PP1 / mRNA_PP1	Differential syn thesis of mRNA Accession No. : 95	compartment_1 Pathway No. : 1116	1.08	0.05	4	explicit E-S complex	Substrate Nucleotides Product PP1mRNA_clx

Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
This Copyright is applied to ensure that the contents of this database remain freely available. Please see FAQ for details.