| Name | Differential synthesis of mRNA |
| Accession Type | Network |
| Transcriber | Pragati Jain and Upinder S. Bhalla, NCBS |
| Developer | Pragati Jain and Upinder S. Bhalla, NCBS |
| Entry Date (YYYY-MM-DD) | 2014-06-10 00:00:00 |
| Species | General Mammalian/Neuronal |
| Tissue | Neuronal |
| Cell Compartment | Surface,Cytosol, Nucleus |
| Source | Peer-reviewed publication,Book |
| Methodology | Quantitative match to experiments,Approximate implementation,Qualitative,Qualitative |
| Model Implementation | Approximate implementation |
| Model Validation | Approximates original data |
| Notes | The model consists of three major pathways: Calcium-calmodulin dependent protein kinase IV (CaMKIV), Mitogen-activated protein kinase (MAPK) and Protein Phosphatase 1 (PP1). Each of these converged on CREB activation. We also modeled further interactions with Transducer of regulated CREB activity 1 (TORC1) and the protein kinase A (PKA) pathway. |
Differential syn
