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Molecule List for pathway AC (Pathway Number 221) in Accession MAPK_network_2003 (Accession Number 50) |
Default ordering is done according to Pathway Number. Table headers can be used for changing the default ordering.  arrow indicates that ordering is done according to ascending or descending order.The entries are grouped according to Pathway Number and are alternately color coded using  and  color. |
| Name | Accession Type | Initial Conc. (uM) | Volume (fL) | Buffered | Sum Total Of | |||
| 1 | PDE1 | Network | 2 | 1000 | No | - | ||
| CaM-Dependent PDE. Amount calculated from total rate in brain vs. specific rate. | ||||||||
| 2 | cAMP-PDE* | Network | 0 | 1000 | No | - | ||
| This form has about 2X activity as plain PDE. See Sette et al JBC 269:28 18271-18274 1994. | ||||||||
| 3 | cAMP-PDE | Network | 0.45 | 1000 | No | - | ||
| The levels of the PDE are not known at this time. However, enough kinetic info and info about steady-state levels of cAMP etc are around to make it possible to estimate this. | ||||||||
| 4 | CaM.PDE1 | Network | 0 | 1000 | No | - | ||
| Activity up 6x following Ca-CaM binding. | ||||||||
| 5 | ATP | Network | 5000 | 1000 | Yes | - | ||
| ATP is present in all cells between 2 and 10 mM. See Lehninger. | ||||||||
| 6 | AMP | Network | 325490 | 0.0016667 | No | - | ||
| 7 | AC2-Gs | Network | 0 | 1000 | No | - | ||
| 8 | AC2*-Gs | Network | 0 | 1000 | No | - | ||
| 9 | AC2* | Network | 0 | 1000 | No | - | ||
| This version is activated by Gs and by a betagamma and phosphorylation. | ||||||||
| 10 | AC2 | Network | 0.015 | 1000 | No | - | ||
| Starting at 0.015 uM. | ||||||||
| 11 | AC1-Gs | Network | 0 | 1000 | No | - | ||
| 12 | AC1-CaM | Network | 0 | 1000 | No | - | ||
| This version of cyclase is Calmodulin activated. Gs stims it but betagamma inhibits. | ||||||||
| 13 | AC1 | Network | 0.02 | 1000 | No | - | ||
| Starting conc at 20 nM. | ||||||||