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Accession Type:
Network
S6K
Shared_Object_
S6K
 Molecule
 Enzyme
 Reaction
mTOR_model
S6Kinase

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Enzyme List for pathway Shared_Object_S6K (Pathway Number 1087)

 Molecule Name/
Site Name
Km (uM) kcat (1/s)Ratio
(k2/k3)
Enzyme TypeSubstrate Product
1 Enzyme Activity:
basal

Enzyme Molecule:
40S_basal
0.2500030.14explicit E-S complex40S_inact
40S
2 Enzyme Activity:
cluster_
phospho_S6K

Enzyme Molecule:
MAPK*
17.299814explicit E-S complexS6K
S6K*
3 Enzyme Activity:
dephosp_S6K

Enzyme Molecule:
PP2A
8.8000914explicit E-S complexS6K_thr-252
S6K_thr-412
4 Enzyme Activity:
dephos_clus_S6K

Enzyme Molecule:
PP2A
8.8000914explicit E-S complexS6K*
S6K
5 Enzyme Activity:
dephos_S6K

Enzyme Molecule:
PP2A
8.8000914explicit E-S complexS6K_thr-412
S6K*
6 Enzyme Activity:
S6K_phospho

Enzyme Molecule:
PDK1
1014explicit E-S complexS6K_thr-412
S6K_thr-252
7 Enzyme Activity:
S6K_phospho

Enzyme Molecule:
TOR_Rheb-GTP_
clx
0.7999740.064explicit E-S complexS6K*
S6K_thr-412
8 Enzyme Activity:
S6_phospho

Enzyme Molecule:
S6K_thr-252
0.2500030.14explicit E-S complex40S_inact
40S


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