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Pathway
MAPK_Asthagiri_
no_fb
MAPK_Asthagiri_
no_fb
Molecule
Enzyme
Reaction
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Model
Molecule List for pathway
MAPK_Asthagiri_no_fb
(Pathway Number 192)
Name
Initial Conc. (uM)
td>
Volume (fL)
Buffered
1
A1
0.0427
390
No
First adaptor protein. Tot.no. 10^4 no./cell from Asthagiri and Lauffenburger 2001
2
A1A2
0
390
No
Adaptor protein heterodimer from Asthagiri and Lauffenburger 2001.
3
A2
0.0427
390
No
Second adaptor protein. Tot.no. 10^4 no./cell from
Anand R. Asthagiri and Douglas A. Lauffenburger (2001 Mar-Apr) Biotechnol Prog. 17(2):227-39
4
C
0
390
No
Ligand bound receptor from
Anand R. Asthagiri and Douglas A. Lauffenburger (2001 Mar-Apr) Biotechnol Prog. 17(2):227-39
5
C*
0
390
No
Activated form of receptor from
Anand R. Asthagiri and Douglas A. Lauffenburger (2001 Mar-Apr) Biotechnol Prog. 17(2):227-39
6
C*A1
0
390
No
Adaptor protein bound activated receptor from
Anand R. Asthagiri and Douglas A. Lauffenburger (2001 Mar-Apr) Biotechnol Prog. 17(2):227-39
7
C2
0
390
No
Dimer formed by receptor binding from
Anand R. Asthagiri and Douglas A. Lauffenburger (2001 Mar-Apr) Biotechnol Prog. 17(2):227-39
8
E0*
0
390
No
9
E1
0.0427
390
No
E1^T = 10^4 no./cell from
Anand R. Asthagiri and Douglas A. Lauffenburger (2001 Mar-Apr) Biotechnol Prog. 17(2):227-39
10
E1*
0
390
No
11
E2
0.0427
390
No
E2^T =10^4 no./cell from
Anand R. Asthagiri and Douglas A. Lauffenburger (2001 Mar-Apr) Biotechnol Prog. 17(2):227-39
12
E2*
0
390
No
13
E3
0.0427
390
No
E3^T =10^4 no./cell from
Anand R. Asthagiri and Douglas A. Lauffenburger (2001 Mar-Apr) Biotechnol Prog. 17(2):227-39
14
E3*
0
390
No
15
E4
0.0427
390
No
E4^T =10^4 no./cell from
Anand R. Asthagiri and Douglas A. Lauffenburger (2001 Mar-Apr) Biotechnol Prog. 17(2):227-39
16
E4*
0
390
No
17
E5
0.0427
390
No
E5^T = 10^4 no./cell from
Anand R. Asthagiri and Douglas A. Lauffenburger (2001 Mar-Apr) Biotechnol Prog. 17(2):227-39
18
E5*
0
390
No
19
L
0.03
390
Yes
L CoInit = buffered at 0.03 uM from
Anand R. Asthagiri and Douglas A. Lauffenburger (2001 Mar-Apr) Biotechnol Prog. 17(2):227-39
20
P1
0.0214
390
No
Deactivating enzyme, P1^T = 5000 no./cell from
Anand R. Asthagiri and Douglas A. Lauffenburger (2001 Mar-Apr) Biotechnol Prog. 17(2):227-39
21
P2
0.0214
390
No
Deactivating enzyme P2^T = 5000 no./cell. from
Anand R. Asthagiri and Douglas A. Lauffenburger (2001 Mar-Apr) Biotechnol Prog. 17(2):227-39
22
P3
0.0214
390
No
Deactivating enzyme P3^T = 5000 no./cell from
Anand R. Asthagiri and Douglas A. Lauffenburger (2001 Mar-Apr) Biotechnol Prog. 17(2):227-39
23
P4
0.0214
390
No
Deactivating enzyme P4^T = 5000 no./cell. from
Anand R. Asthagiri and Douglas A. Lauffenburger (2001 Mar-Apr) Biotechnol Prog. 17(2):227-39
24
P5
0.0214
390
No
Deactivating enzyme P5^T = 5000 no./cell from
Anand R. Asthagiri and Douglas A. Lauffenburger (2001 Mar-Apr) Biotechnol Prog. 17(2):227-39
25
R
0.4274
390
No
R nInit = 10^5 no./cell from
Anand R. Asthagiri and Douglas A. Lauffenburger (2001 Mar-Apr) Biotechnol Prog. 17(2):227-39
Pathway Details
Molecule List
Enzyme List
Reaction List
Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
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