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Reaction List for pathway Growth (Pathway Number 1069) |
| Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reactions is not considered. |
| Name | Kf | Kb | Kd | tau | Substrate | Product | |
| 1 | H1 | 0.2 (uM^-4 s^-1) | 125 (s^-1) | - | - | Rb_dup Rb_dup Rb_dup Rb_dup Heaviside_inh | Heaviside_mid |
| This reaction approximates the Heaviside function. What it does is to present a high-order dependence on Rb_P, such that when Rb_P is about 0.8 of the total It is supposed to be 1 if Rb_hypo <= 0.8 Rb_tot. Here we have Rb_P = Rb_tot - Rb_hypo, so we want the outcome to be 1 if Rb_P > 0.2 We use a 4th order step to get a sharper transition. Use a sumtotal so that Rb_P itself is not affected. 29 March 2005. Now this is part of a 2-step heaviside function, perhaps more biologically motivated. Also the input is Rb. 18 Apr 2005. Speeded up 10 fold. Also note that the critical amount of Rb is Rb/Rbtot. Since Rbtot = 10, the Kd should be 8, not 0.8. | |||||||
| 2 | k28 | 0.2 (s^-1) | 0 (s^-1) | - | - | GM | degraded |
| k28 = 0.2 | |||||||
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