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Reaction List for pathway E2F (Pathway Number 1076) |
| Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reactions is not considered. |
|   | Name | Kf | Kb | Kd | tau | Substrate | Product |
| 1 | k22_23_prime | 1 (s^-1) | 0.005 (s^-1) | Keq = 0.005(uM) | 0.995sec | E2FAP | E2FA |
| k22 is the forward rate of 1 k23_prime is the backward rate of 0.005 | |||||||
| 2 | k22_23_prime.Rb | 1 (s^-1) | 0.005 (s^-1) | Keq = 0.005(uM) | 0.995sec | E2FAP.Rb | E2FA.Rb |
| k22 is the forward rate of 1 k23_prime is the backward rate of 0.005 | |||||||
| 3 | k26 | 10 (uM^-1 s^-1) | 200 (s^-1) | Kd(bf) = 20.0001(uM) | - | Rb E2FA | E2FA.Rb |
| k26 = 10, k26r =200 Unless k26 = 10000. There is a period in the paper but it may be a typo. The form of the equation is complex, but if k26 is large then there is more E2F:Rb, so that is the forward reaction here. | |||||||
| 4 | k26_P | 10 (uM^-1 s^-1) | 200 (s^-1) | Kd(bf) = 20.0001(uM) | - | Rb E2FAP | E2FAP.Rb |
| Same as k26, but acting on the phosph form. | |||||||
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