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Reaction List for pathway MAPK_Asthagiri_no_fb (Pathway Number 192) |
| Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reactions is not considered. |
|   | Name | Kf | Kb | Kd | tau | Substrate | Product |
| 1 | A1-bind-A2 | 5.0001 (uM^-1 s^-1) | 0.5 (s^-1) | Kd(bf) = 0.1(uM) | - | A2 A1 | A1A2 |
| Kc12 and Kd12 are 3*10^8 M-1 min-1 and 0.5/sec from Asthagiri and Lauffenburger 2001. | |||||||
| 2 | C*-bind-A1 | 5.0001 (uM^-1 s^-1) | 0.5 (s^-1) | Kd(bf) = 0.1(uM) | - | C* A1 | C*A1 |
| Kf1 is 3*10^8 M-1 min-1 and Kr1 is 0.5/sec from Anand R. Asthagiri and Douglas A. Lauffenburger (2001 Mar-Apr) Biotechnol Prog. 17(2):227-39 | |||||||
| 3 | C*-bind-A1A2 | 5.0001 (uM^-1 s^-1) | 0.5 (s^-1) | Kd(bf) = 0.1(uM) | - | A1A2 C* | E0* |
| Kf12 and Kr12 are 3*10^8 M-1 min-1 and 0.5/sec from Anand R. Asthagiri and Douglas A. Lauffenburger (2001 Mar-Apr) Biotechnol Prog. 17(2):227-39 | |||||||
| 4 | C*A1-bind-A2 | 5.0001 (uM^-1 s^-1) | 0.5 (s^-1) | Kd(bf) = 0.1(uM) | - | C*A1 A2 | E0* |
| kf2 and kr2 are 3*10^8 M-1 min-1 and 0.5/sec from Anand R. Asthagiri and Douglas A. Lauffenburger (2001 Mar-Apr) Biotechnol Prog. 17(2):227-39 | |||||||
| 5 | C-dimer | 1 (uM^-1 s^-1) | 1 (s^-1) | Keq = 1(uM) | - | C C | C2 |
| Kc is 6*10^7 M-1 min-1 and Ku is 60 min-1 from Anand R. Asthagiri and Douglas A. Lauffenburger (2001 Mar-Apr) Biotechnol Prog. 17(2):227-39 | |||||||
| 6 | C2-phos | 0.833 (s^-1) | 0.0833 (s^-1) | Keq = 0.1(uM) | 1.091sec | C2 | C* |
| Kc+ is 50min-1 and Kc- is 5min-1 from Anand R. Asthagiri and Douglas A. Lauffenburger (2001 Mar-Apr) Biotechnol Prog. 17(2):227-39 | |||||||
| 7 | L-bind-R | 0.1666 (uM^-1 s^-1) | 0.005 (s^-1) | Kd(bf) = 0.03(uM) | - | L R | C |
| Kf = 10^7/M-1 min-1 and Kr is 0.3 min-1 from Anand R. Asthagiri and Douglas A. Lauffenburger (2001 Mar-Apr) Biotechnol Prog. 17(2):227-39 | |||||||
| Pathway Detail | Molecule List | Enzyme List | Reaction List |