| | Lac_gene |
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Reaction List for pathway TetR_gene (Pathway Number 297) | Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reactions is not considered. |   | Name | Kf | Kb | Kd | tau | Substrate | Product | 1 |
TetR_ degradation | 0.0167 (s^-1) | 0 (s^-1) | - | - | TetR
| Degraded_TetR
| | This reaction denotes the degradation of Tet R the half life of which is ten minutes. t1/2 = 0.693/k where k denotes kf Note: Rates had to be scaled by 1.4 to get appropriate levels Elowitz, M. et al. (2000) Nature 403:335-338 | 2 |
tetR_mRNA_ degradation | 0.0058 (s^-1) | 0 (s^-1) | - | - | tetR_mRNA
| Degraded_tetR_ mRNA
| | This reaction denotes the degradation of the tetR m-RNA, the half life of which is two minutes. t1/2 = 0.693/k where k denotes kf Elowitz, M. et al. (2000) Nature 403:335-338 | 3 |
TetR_operator_ inhibition_ reaction | 1000.01 (uM^-1 s^-1) | 224 (s^-1) | Kd(bf) = 0.224(uM) | - | TetR_operator Lac
| TetR_operator_ 1st_bound
| | It signifies the first binding of the repressor with the operator Kf = 1 /nM/sec Kb = 224 /sec Box 1 Elowitz, M. et al. (2000) Nature 403:335-338 | 4 |
TetR_operator_ inhibition_ reaction[1] | 1000.01 (uM^-1 s^-1) | 9 (s^-1) | Kd(bf) = 0.009(uM) | - | TetR_operator_ 1st_bound Lac
| TetR_operator_ 2nd_bound
| | It signifies the second binding of the repressor with the operator Kf = 1 /nM/sec Kb = 9 /sec Box 1 Elowitz, M. et al. (2000) Nature 403:335-338 |
Pathway Details Molecule List Enzyme List Reaction List
| Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR This Copyright is applied to ensure that the contents of this database remain freely available. Please see FAQ for details. |
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