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Reaction List for pathway Cytoplasm (Pathway Number 306) |
| Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reactions is not considered. |
| Name | Kf | Kb | Kd | tau | Substrate | Product | |
| 1 | NTF2_binding | 1 (uM^-1 s^-1) | 0.1 (s^-1) | Kd(bf) = 0.1(uM) | - | NTF2 mic | NTF2-GDP.Ran |
| Binding of NTF2 to cytoplasmic fraction of GDP.Ran Kd = 100 nM Catherine Chaillan-Huntington et al (2000) J.Biol.Chem. 275(8):5874-5879. call /kinetics/Cytoplasm/RanGTP_binding/notes LOAD Binding of cytoplasmic fraction of RanGTP to RanBP1 Kf = 3.0e+05 /M/sec = 0.3 /uM/sec Kb = 4.0e-04 /sec Carolina I. Villa Braslavsky et al (2000) Biochemistry 39(38):11629-11639. Supplementary Table A Gorlich D et al (2003) EMBO J 22(5):1088-1100 | |||||||
| 2 | NTF2_ dissociation | 0.48 (s^-1) | 0 (#^-1 s^-1) | Not applicable** | - | NTF2-GDP.Ran | NTF2 GDP.Ran-nuclear |
| Approximation of rates to match the kinetics described by Gorlich D et al (2003) EMBO J 22(5):1088-1100 | |||||||
| 3 | RanGTP_binding | 18.0004 (uM^-1 s^-1) | 0.0004 (s^-1) | Kd(bf) = 0(uM) | - | mic RanBP1 | RanBP1.RanGTP |
| Pathway Detail | Molecule List | Enzyme List | Reaction List |