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Reaction List for pathway SGC (Pathway Number 88)

Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reactions is not considered.
  Name KfKbKdtauSubstrateProduct
1 cGMPbindPKG10
(uM^-1 s^-1)		0.5
(s^-1)		Kd(bf) = 0.05(uM)-cGMP
PKG
cGMP.PKG
  Kd - 0.05uM Shinya Kuroda, 2001, J.Neurosci., 21(15):5693-5702.
2 degradeNO0.673
(s^-1)		0
(s^-1)		--NO
NOdegrade
  degradation of NO ... kf - 0.673 / sec .... Shinya Kuroda, J.Neurosci, 2001, 21(15):5693-5702
3 dephosphory0.0001
(s^-1)		0
(s^-1)		--Gsub*
Gsub
  kf - 0.0001/sec Shinya Kuroda, J.Neurosci, 2001, 21(15):5693-5702 ... and thru personal correspondence ...
4 NObindGC0.01
(uM^-1 s^-1)		0.0025
(s^-1)		Kd(bf) = 0.25(uM)-NO
GC
NO_GC
  Kd 250 nM (Stone and Marletta, 1996).. kf - 0.01 kb - 0.0025 Shinya Kuroda, J.Neurosci, 2001, 21(15):5693-5702 ...
5 PP2AbindGsub*1
(uM^-1 s^-1)		0.27
(s^-1)		Kd(bf) = 0.27(uM)-PP2A
Gsub*
PP2A_Gsub*
  Kd - 0.27 uM Shinya Kuroda, J.Neurosci, 2001, 21(15):5693-5702.
Pathway DetailMolecule ListEnzyme ListReaction List