| Name | fig3_CaMKII |
| Accession Type | Network |
| Transcriber | Upinder S. Bhalla, NCBS |
| Developer | Upinder S. Bhalla, NCBS |
| Entry Date (YYYY-MM-DD) | 2001-11-07 00:00:00 |
| Species | Generic mammalian |
| Tissue | Neuronal |
| Cell Compartment | Synapse |
| Source | Bhalla US and Iyengar R. Science (1999) 283(5400):381-7. ( peer-reviewed publication ) |
| Methodology | Quantitative match to experiments, Qualitative |
| Model Implementation | Exact GENESIS implementation |
| Model Validation | Approximates orginal data, Quantitatively predicts new data |
| Notes | This is the model file for figure 3 from Bhalla US and Iyengar R. Science (1999) 283(5400):381-7. It is a model of the Ca activation of CaMKII and other CaM-activated enzymes. It includes the regulatory phosphatases PP1 and PP2B (Calcineurin) acting on CaMKII and also includes CaM-activated adenylyl cyclase and PKA in the synapse.
Demonstration script files for generating the figures in the paper, including figure 3, are available here. |
