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Molecule Parameter List for int4

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by color.
Statistics
int4 participated asMoleculeSum total ofEnzymeSubstrate of an enzymeProduct of an enzymeSubstrate in ReactionProduct in Reaction
No. of occurrences1010000

Accession and Pathway Details
Accession NameAccession No.Accession TypePathway Link
MAPK_osc27Pathway
MAPK 
This MAPK model is based on Boris N. Kholodenko Eur J Biochem. (2000) 267(6):1583-8 for data from Xenopus oocytes extracts.

int4 acting as a Molecule in  
MAPK_osc Network
NameAccession NamePathway NameInitial Conc.
(uM)
Volume
(fL)
Buffered
int4MAPK_osc
Accession No. : 27
MAPK
Pathway No. : 139
0.0010.0016667No
This intermediate enzyme catalyses the dephosphorylation of MAPK-PP to MAPK-P. The concentration is 1nM. from Kholodenko, 2000

int4 acting as an Enzyme in  
MAPK_osc Network
Enzyme Molecule /
Enzyme Activity
Accession NamePathway NameKm (uM)kcat (s^-1)RatioEnzyme TypeReagents
int4 /
9
MAPK_osc
Accession No. : 27
MAPK
Pathway No. : 139
0.01499970.54Classical Michaelis-Menten
V = Etot.S.Kcat/Km+S
Substrate
MAPK-PP

Product
MAPK-P
The Km is 15nM and Vmax is 0.5nM.s-1 from Kholodenko, 2000



Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
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