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Molecule Parameter List for Ca25-Cal

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by color.
Statistics
Ca25-Cal participated asMoleculeSum total ofEnzymeSubstrate of an enzymeProduct of an enzymeSubstrate in ReactionProduct in Reaction
No. of occurrences1000011

Accession and Pathway Details
Accession NameAccession No.Accession TypePathway Link
  • NonOsc_Ca_
    IP3metabolism
    		• 31Network
    MIPP,  CaMKII,  CaM,  
    PKC,  IP3-3K,  CaRegulation,  
    Gq,  PLCbeta,  134_dephos,  
    145_dephos,  IP4-system,  IHP-system,  
    1345_dephos 
    This network models detailed metabolism of Ins(145)P3, integrated with GPCR mediated PLCbeta activation and Ca release by the InsP3 receptor in the neuron. It is similar to the NonOsc_Ca_IP3metab model (accession 23) except that some enzymes have been modified to have reversible kinetics rather than Michaelis-Menten kinetics. These modified enzymes belong to the groups: IP4-system, IP3-3K, 145_dephos and 134_dephos. Mishra J, Bhalla US. Biophys J. 2002 Sep;83(3):1298-316.

    Ca25-Cal acting as a Molecule in      NonOsc_Ca_IP3metabolism Network
    NameAccession NamePathway NameInitial Conc.
    (uM)    		Volume
    (fL)    		Buffered
    Ca25-Cal
  • NonOsc_Ca_
    IP3metabolism
    Accession No. : 31
    		• CaRegulation
    Pathway No. : 149    		0160No
    Calsequestrin with 25 Ca molecules bound

    Ca25-Cal acting as a Substrate in a reaction in      NonOsc_Ca_IP3metabolism Network
    Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider.
    NameAccession NamePathway NameKfKbKdtauReagents
    Ca30-bind-Cal
  • NonOsc_Ca_
    IP3metabolism
    Accession No. : 31
    		• CaRegulation
    Pathway No. : 149    		0.0005
    (uM^-5 s^-1)    		1
    (s^-1)    		--Substrate
    Ca-sequester
    Ca-sequester
    Ca-sequester
    Ca-sequester
    Ca-sequester
    Ca25-Cal

    Product
    Ca30-Cal
    There are actually 5 Ca-sequester substrates for this reaction, along with Ca25-Cal. Due to system limitations only four are entered.

    Ca25-Cal acting as a Product in a reaction in      NonOsc_Ca_IP3metabolism Network
    Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider.
    NameAccession NamePathway NameKfKbKdtauReagents
    Ca25-bind-Cal
  • NonOsc_Ca_
    IP3metabolism
    Accession No. : 31
    		• CaRegulation
    Pathway No. : 149    		0.0005
    (uM^-5 s^-1)    		1
    (s^-1)    		--Substrate
    Ca-sequester
    Ca-sequester
    Ca-sequester
    Ca-sequester
    Ca-sequester
    Ca20-Cal

    Product
    Ca25-Cal
    There are actually 5 Ca-sequester substrates for this reaction, along with Ca20-Cal. Due to system limitations only four are entered.


    Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
    This Copyright is applied to ensure that the contents of this database remain freely available. Please see FAQ for details.