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Molecule Parameter List for tot_autonomous_CaMKII | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network. The text color of a molecule is highlighted by  color. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Statistics | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| tot_autonomous_CaMKII participated as | Molecule | Sum total of | Enzyme | Substrate of an enzyme | Product of an enzyme | Substrate in Reaction | Product in Reaction |
| No. of occurrences | 1 | 1 | 2 | 0 | 0 | 0 | 0 |
Accession and Pathway Details |
| Accession Name | Accession No. | Accession Type | Pathway Link |
| CaMKII_2003 | 49 | Network | Shared_Object_CaMKII_2003, CaMKII, CaM, PP1, PP2B |
| Model of regulation of CaMKII by Calcium, including parallel excitatory input from CaM and inhibitory input from PP1 as regulated by Calcineurin and PKA. Cell type: neuronal. Bhalla US. Biophys J. 2004 Aug;87(2):733-44. | |||
tot_autonomous_CaMKII acting as a Molecule in CaMKII_2003 Network
| Name | Accession Name | Pathway Name | Initial Conc. (uM) | Volume (fL) | Buffered | |
| tot_autonomous_CaMKII | CaMKII_2003 Accession No. : 49 | CaMKII Pathway No. : 202 | 0 | 1000 | No | |
tot_autonomous_CaMKII acting as a Summed Molecule in CaMKII_2003 Network
| Accession Name | Pathway Name | Target | Input |
| CaMKII_2003 Accession No. : 49 | CaMKII Pathway No. : 202 | tot_autonomous_CaMKII | CaMKII-thr286 CaMKII*** |
tot_autonomous_CaMKII acting as an Enzyme in CaMKII_2003 Network
| Enzyme Molecule / Enzyme Activity | Accession Name | Pathway Name | Km (uM) | kcat (s^-1) | Ratio | Enzyme Type | Reagents | |
| 1 | CaMKII / auton_305 | CaMKII_2003 Accession No. : 49 | CaMKII Pathway No. : 202 | 175.003 | 6 | 4 | explicit E-S complex | Substrate CaMKII-thr286 Product CaMKII*** |
| See Hanson and Schulman again, for afterburst rates of phosph. | ||||||||
| 2 | CaMKII / auton_286 | CaMKII_2003 Accession No. : 49 | CaMKII Pathway No. : 202 | 174.997 | 0.5 | 4 | explicit E-S complex | Substrate CaMKII-CaM Product aM |