NCBS Home page
Accession List
Pathway List
Search
Authorized Users
Help
News archives

Enter a Search String

Special character and space not allowed in the query term. Search string should be at least 2 characters long.
Search in: Search for Match By

Molecule Parameter List for CaMKII-thr286-PSD

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by color.
Statistics
CaMKII-thr286-PSD participated asMoleculeSum total ofEnzymeSubstrate of an enzymeProduct of an enzymeSubstrate in ReactionProduct in Reaction
No. of occurrences1203310

Accession and Pathway Details
Accession NameAccession No.Accession TypePathway Link
  • CaMKII_noPKA_
    model3
  • 62Network
    Shared_Object_CaMKII_noPKA_model3 CaMKII CaM 
    PP1 PP2B PP1_PSD 
    This is the model of CaMKII bistability, model 3. It exhibits bistability in CaMKII activation due to autophosphorylation at the PSD and local saturation of PP1. This version of model 3 does not include the full PKA regulatory pathway, and instead has a predefined initial amount of active PKA.

    CaMKII-thr286-PSD acting as a Molecule in  
    CaMKII_noPKA_model3 Network
    NameAccession NamePathway NameInitial Conc.
    (uM)
    Volume
    (fL)
    Buffered
    CaMKII-thr286-PSD
  • CaMKII_noPKA_
    model3

    Accession No. : 62
  • Shared_Object_
    CaMKII_noPKA_
    model3

    Pathway No. : 257
  • 00.01No

    CaMKII-thr286-PSD acting as a Summed Molecule in  
    CaMKII_noPKA_model3 Network
     Accession NanePathway NameTargetInput
    1
  • CaMKII_noPKA_
    model3

    Accession No. : 62
  • Shared_Object_
    CaMKII_noPKA_
    model3

    Pathway No. : 257
  • tot-auto-PSD
  • CaMKII-thr286-PS
    D

    CaMKII***-PSD
  • basal_CaMKII_
    PSD

  • 2
  • CaMKII_noPKA_
    model3

    Accession No. : 62
  • Shared_Object_
    CaMKII_noPKA_
    model3

    Pathway No. : 257
  • 286P-PSD
  • CaMKII-thr286-Ca
    M-PSD

  • CaMKII-thr286-PS
    D


  • CaMKII-thr286-PSD acting as a Substrate for an Enzyme in  
    CaMKII_noPKA_model3 Network
     Enzyme Molecule /
    Enzyme Activity
    Accession NamePathway NameKm (uM)kcat (s^-1)RatioEnzyme TypeReagents
    1tot-auto-PSD  /
    auton-305-PSD
  • CaMKII_noPKA_
    model3

    Accession No. : 62
  • Shared_Object_
    CaMKII_noPKA_
    model3

    Pathway No. : 257
  • 50064explicit E-S complexSubstrate
  • CaMKII-thr286-PS
    D


    Product
    CaMKII***-PSD
  • 2PP1-active_PSD  /
    Deph-thr286b
  • CaMKII_noPKA_
    model3

    Accession No. : 62
  • Shared_Object_
    CaMKII_noPKA_
    model3

    Pathway No. : 257
  • 2.000010.24explicit E-S complexSubstrate
  • CaMKII-thr286-PS
    D


    Product
    CaMKII-PSD
  • 3
  • tot-CaM-CaMKII-P
    SD
      /
    CaM-act-305-PSD
  • CaMKII_noPKA_
    model3

    Accession No. : 62
  • Shared_Object_
    CaMKII_noPKA_
    model3

    Pathway No. : 257
  • 32064explicit E-S complexSubstrate
  • CaMKII-thr286-PS
    D


    Product
    CaMKII***-PSD

  • CaMKII-thr286-PSD acting as a Product of an Enzyme in  
    CaMKII_noPKA_model3 Network
     Enzyme Molecule /
    Enzyme Activity
    Accession NamePathway NameKm (uM)kcat (s^-1)RatioEnzyme TypeReagents
    1tot-auto-PSD  /
    auton-autoph
  • CaMKII_noPKA_
    model3

    Accession No. : 62
  • Shared_Object_
    CaMKII_noPKA_
    model3

    Pathway No. : 257
  • 500.00524explicit E-S complexSubstrate
    CaMKII-PSD

    Product
  • CaMKII-thr286-PS
    D

  • 2PP1-active_PSD  /
    Deph-thr305
  • CaMKII_noPKA_
    model3

    Accession No. : 62
  • Shared_Object_
    CaMKII_noPKA_
    model3

    Pathway No. : 257
  • 2.000010.24explicit E-S complexSubstrate
    CaMKII***-PSD

    Product
  • CaMKII-thr286-PS
    D

  • 3
  • tot-CaM-CaMKII-P
    SD
      /
    CaM_act_autoph
  • CaMKII_noPKA_
    model3

    Accession No. : 62
  • Shared_Object_
    CaMKII_noPKA_
    model3

    Pathway No. : 257
  • 320.00224explicit E-S complexSubstrate
    CaMKII-PSD

    Product
  • CaMKII-thr286-PS
    D


  • CaMKII-thr286-PSD acting as a Substrate in a reaction in  
    CaMKII_noPKA_model3 Network
    Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider.
    NameAccession NamePathway NameKfKbKdtauReagents
  • CaMKII-thr286-bi
    nd-CaM-PSD
  • CaMKII_noPKA_
    model3

    Accession No. : 62
  • Shared_Object_
    CaMKII_noPKA_
    model3

    Pathway No. : 257
  • 1000.02
    (uM^-1 s^-1)
    0.1
    (s^-1)
    Kd(bf) = 0.0001(uM)-Substrate
    CaM-Ca4-PSD
  • CaMKII-thr286-PS
    D


    Product
  • CaMKII-thr286-Ca
    M-PSD

  • Same values as for the main compartment Can the main compartment pool of Ca/CaM be used?



    Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
    This Copyright is applied to ensure that the contents of this database remain freely available. Please see FAQ for details.