| Name | AMPAR_CaMKII_strong_coupling |
| Accession Type | Network |
| Transcriber | Upinder S. Bhalla, NCBS |
| Developer | Arnold Hayer and Upinder S. Bhalla, NCBS |
| Entry Date (YYYY-MM-DD) | 2005-07-19 00:00:00 |
| Species | General Mammalian |
| Tissue | Neuronal |
| Cell Compartment | Synaptic Spine, Postsynaptic Density |
| Source | Hayer A, Bhalla US PLoS Comput Biol. 2005 Jul;1(2):137-54. Epub 2005 Jul 29. ( Peer-reviewed publication ) |
| Methodology | Quantitative match to experiments, Qualitative |
| Model Implementation | Exact GENESIS implementation |
| Model Validation | Replicates original data , Approximates original data |
| Notes | This is a model of tight coupling between the AMPAR trafficking bistability, and the CaMKII autophosphorylation bistability. In this model, the CaMKII activity is self sustaining only when AMPAR is turned on. Further, CaMKII turns on when AMPAR is turned on. |
