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Molecule Parameter List for Blocked-rec-Gq

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by color.
Statistics
Blocked-rec-Gq participated asMoleculeSum total ofEnzymeSubstrate of an enzymeProduct of an enzymeSubstrate in ReactionProduct in Reaction
No. of occurrences1000001

Accession and Pathway Details
Accession NameAccession No.Accession TypePathway Link
  • Ajay_Bhalla_
    2004_PKM_Tuning
  • 76Network
    PKC Shared_Object_Ajay_Bhalla_2004_PKM_tuning PLA2 
    PLCbeta Gq MAPK 
    Ras EGFR Sos 
    PLC_g CaMKII CaM 
    PP1 PP2B PKA 
    AC PKM 
    This model is taken from the Ajay SM, Bhalla US. Eur J Neurosci. 2004 Nov;20(10):2671-80. This is the reference feedforward model from Figure 8a.

    Blocked-rec-Gq acting as a Molecule in  
    Ajay_Bhalla_2004_PKM_Tuning Network
    NameAccession NamePathway NameInitial Conc.
    (uM)
    Volume
    (fL)
    Buffered
    Blocked-rec-Gq
  • Ajay_Bhalla_
    2004_PKM_Tuning

    Accession No. : 76
  • Gq
    Pathway No. : 316
    01.5No

    Blocked-rec-Gq acting as a Product in a reaction in  
    Ajay_Bhalla_2004_PKM_Tuning Network
    Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider.
    NameAccession NamePathway NameKfKbKdtauReagents
  • Antag-bind-Rec-G
    q
  • Ajay_Bhalla_
    2004_PKM_Tuning

    Accession No. : 76
  • Gq
    Pathway No. : 316
    60.0003
    (uM^-1 s^-1)
    0.01
    (s^-1)
    Kd(bf) = 0.0002(uM)-Substrate
    Rec-Gq
    mGluRAntag

    Product
    Blocked-rec-Gq
    The rate consts give a total binding affinity of only



    Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
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