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Accession Type:
Network
Ajay_Bhalla_
2004_PKM_Tuning
PKC
Shared_Object_
Ajay_Bhalla_
2004_PKM_tuning
PLA2
PLCbeta
Gq
MAPK
Ras
EGFR
Sos
PLC_g
CaMKII
 Molecule
 Enzyme
 Reaction
CaM
PP1
PP2B
PKA
AC
PKM

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Parameters for CaMKII (Pathway Number 322)

Pathway Layout

Pathway Basic Parameters

Pathway NameCaMKII
Pathway Entry Number 322
Accession Number 76
Accession Name Ajay_Bhalla_2004_PKM_Tuning
Species Rat
Tissue Hippocampal CA1
CellCompartmentDendrite
Related Pathways 13, 26, 80, 106, 121, 145, 159, 174, 202, 216, 235, 245, 258, 264, 272, 282, 339, 357
Notes Main reference here is the review by Hanson and Schulman, Ann Rev Biochem 1992 vol 61 pp 559-601. Most of the mechanistic details and a few constants are derived from there. Many kinetics are from Hanson and Schulman JBC 267:24 17216-17224 1992. The enzs look a terrible mess. Actually it is just 3 reactions for diff sites, by 4 states of CaMKII, defined by the phosph state.

Statistics

8
4
3

Conversion format

This pathway is part of accession 76 and is completely specified in the file acc76.g.
There is no separate files for just this pathway.
FormatFile
Native Format (GENESIS format)    acc76.g   
MATLAB format    acc76.m   
SBML format    acc76.xml   


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Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
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