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Molecule Parameter List for ATP

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network. The text color of a molecule is highlighted by color.

Statistics

ATP participated as	Molecule	Sum total of	Enzyme	Substrate of an enzyme	Product of an enzyme	Substrate in Reaction	Product in Reaction
No. of occurrences	1	0	0	5	0	0	0

Accession and Pathway Details

Accession Name	Accession No.	Accession Type	Pathway Link
Ajay_Bhalla_ 2004_PKM_MKP3_ Tuning	77	Network	Shared_Object_Ajay_Bhalla_2004_PKM_MKP3_Tuning,  PKC,  PLA2,   PLCbeta,  Ras,  Gq,   MAPK,  EGFR,  Sos,   PLC_g,  CaMKII,  CaM,   PP1,  PP2B,  PKA,   AC,  MKP3,  PKM
This model is based on Ajay SM, Bhalla US. Eur J Neurosci. 2004 Nov;20(10):2671-80. This is the feedforward model with MPK3 from figure 8a.

ATP acting as a Molecule in  Ajay_Bhalla_2004_PKM_MKP3_Tuning Network

Name	Accession Name	Pathway Name	Initial Conc. (uM)	Volume (fL)	Buffered
ATP	Ajay_Bhalla_ 2004_PKM_MKP3_ Tuning Accession No. : 77	AC Pathway No. : 344	5000	1.5	Yes
ATP is present in all cells between 2 and 10 mM. See Lehninger.

ATP acting as a Substrate for an Enzyme in  Ajay_Bhalla_2004_PKM_MKP3_Tuning Network

	Enzyme Molecule / Enzyme Activity	Accession Name	Pathway Name	Km (uM)	kcat (s^-1)	Ratio	Enzyme Type	Reagents
1	AC1-CaM  / kenz	Ajay_Bhalla_ 2004_PKM_MKP3_ Tuning Accession No. : 77	AC Pathway No. : 344	20	18	4	explicit E-S complex	Substrate ATP Product cAMP
2	AC2*  / kenz	Ajay_Bhalla_ 2004_PKM_MKP3_ Tuning Accession No. : 77	AC Pathway No. : 344	20.1153	7	4	explicit E-S complex	Substrate ATP Product cAMP
	Reduced Km to match expt data for basal activation of AC2 by PKC. Now k1 = 2.9e-6, k2 = 72, k3 = 18
3	AC2-Gs  / kenz	Ajay_Bhalla_ 2004_PKM_MKP3_ Tuning Accession No. : 77	AC Pathway No. : 344	20	18	4	explicit E-S complex	Substrate ATP Product cAMP
4	AC1-Gs  / kenz	Ajay_Bhalla_ 2004_PKM_MKP3_ Tuning Accession No. : 77	AC Pathway No. : 344	20	18	4	explicit E-S complex	Substrate ATP Product cAMP
5	AC2*-Gs  / kenz	Ajay_Bhalla_ 2004_PKM_MKP3_ Tuning Accession No. : 77	AC Pathway No. : 344	60	54	4	explicit E-S complex	Substrate ATP Product cAMP