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Molecule Parameter List for PKC-DAG-memb* | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network. The text color of a molecule is highlighted by  color. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Statistics | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| PKC-DAG-memb* participated as | Molecule | Sum total of | Enzyme | Substrate of an enzyme | Product of an enzyme | Substrate in Reaction | Product in Reaction |
| No. of occurrences | 1 | 1 | 0 | 0 | 0 | 0 | 1 |
Accession and Pathway Details |
| Accession Name | Accession No. | Accession Type | Pathway Link |
| 3d_fold_model | 8 | Network | Shared_Object_3d_fold_model, PKC, MAPK, PLA2, Ras |
| This model is an annotated version of the synaptic signaling network. The primary reference is Bhalla US and Iyengar R. Science (1999) 283(5400):381-7 but several of the model pathways have been updated Bhalla US, Ram PT, Iyengar R. Science. 2002 Aug 9;297(5583):1018-23. | |||
PKC-DAG-memb* acting as a Molecule in 3d_fold_model Network
| Name | Accession Name | Pathway Name | Initial Conc. (uM) | Volume (fL) | Buffered | |
| PKC-DAG-memb* | 3d_fold_model Accession No. : 8 | PKC Pathway No. : 55 | 0 | 1000 | No | |
PKC-DAG-memb* acting as a Summed Molecule in 3d_fold_model Network
| Accession Name | Pathway Name | Target | Input |
| 3d_fold_model Accession No. : 8 | 3d_fold_model Pathway No. : 54 | PKC-active | PKC-DAG-AA* PKC-Ca-memb* PKC-Ca-AA* PKC-DAG-memb* PKC-basal* PKC-AA* |
| Conc of PKC in brain is about 1 uM (?) | |||
PKC-DAG-memb* acting as a Product in a reaction in 3d_fold_model Network
| Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider. |
| Name | Accession Name | Pathway Name | Kf | Kb | Kd | tau | Reagents |
| PKC-DAG-to-memb | 3d_fold_model Accession No. : 8 | PKC Pathway No. : 55 | 1 (s^-1) | 0.1 (s^-1) | Keq = 0.1(uM) | 0.909sec | Substrate PKC-Ca-DAG Product PKC-DAG-memb* |
| Raise kb from .087 to 0.1 to match data from Shinomura et al. Lower kf from 1.155 to 1.0 to match data from Shinomura et al. | |||||||