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Molecule Parameter List for DRG_2

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network. The text color of a molecule is highlighted by color.

Statistics

DRG_2 participated as	Molecule	Sum total of	Enzyme	Substrate of an enzyme	Product of an enzyme	Substrate in Reaction	Product in Reaction
No. of occurrences	1	2	0	0	0	0	1

Accession and Pathway Details

Accession Name	Accession No.	Accession Type	Pathway Link
Mammalian_cell_ cycle	85	Network	Growth,  CELLDIV,  Rb_grp,   IE_GRP,  CycB_Grp,  Cdc20_Grp,   Cdh1_grp,  E2F,  CycA_Grp,   CycE_grp,  Early_Response_Genes,  Delayed_Response_Genes,   CycD_Grp
This is a fairly complete mass-action reimplementation of the Novak and Tyson mammalian cell cycle model. It is inexact on two counts. First, it replaces many rather abstracted equations with mass action and Michaelis-Menten forms of enzymes. Second, it does not handle the halving of cellular volume at the division point. Within these limitations, the model does most of what the original paper shows including oscillation of the relevant molecules.

DRG_2 acting as a Molecule in  Mammalian_cell_cycle Network

Name	Accession Name	Pathway Name	Initial Conc. (uM)	Volume (fL)	Buffered
DRG_2	Mammalian_cell_ cycle Accession No. : 85	Delayed_ Response_Genes Pathway No. : 1080	0.5	200	No

DRG_2 acting as a Summed Molecule in  Mammalian_cell_cycle Network

	Accession Nane	Pathway Name	Target	Input
1	Mammalian_cell_ cycle Accession No. : 85	Early_Response_ Genes Pathway No. : 1079	DRG_2B	DRG_2
2	Mammalian_cell_ cycle Accession No. : 85	Delayed_ Response_Genes Pathway No. : 1080	DRG_2A	DRG_2

DRG_2 acting as a Product in a reaction in  Mammalian_cell_cycle Network

Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider.

Name	Accession Name	Pathway Name	Kf	Kb	Kd	tau	Reagents
DRG_dimerize	Mammalian_cell_ cycle Accession No. : 85	Delayed_ Response_Genes Pathway No. : 1080	10 (uM^-1 s^-1)	10 (s^-1)	Keq = 1(uM)	-	Substrate DRG_dup DRG_dup Product DRG_2