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Molecule Parameter List for DRG_2

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by color.
Statistics
DRG_2 participated asMoleculeSum total ofEnzymeSubstrate of an enzymeProduct of an enzymeSubstrate in ReactionProduct in Reaction
No. of occurrences1200001

Accession and Pathway Details
Accession NameAccession No.Accession TypePathway Link
  • Mammalian_cell_
    cycle
    		• 85Network
    Growth,  CELLDIV,  Rb_grp,  
    IE_GRP,  CycB_Grp,  Cdc20_Grp,  
    Cdh1_grp,  E2F,  CycA_Grp,  
    CycE_grp,  Early_Response_Genes,  Delayed_Response_Genes,  
    CycD_Grp 
    This is a fairly complete mass-action reimplementation of the Novak and Tyson mammalian cell cycle model. It is inexact on two counts. First, it replaces many rather abstracted equations with mass action and Michaelis-Menten forms of enzymes. Second, it does not handle the halving of cellular volume at the division point. Within these limitations, the model does most of what the original paper shows including oscillation of the relevant molecules.

    DRG_2 acting as a Molecule in      Mammalian_cell_cycle Network
    NameAccession NamePathway NameInitial Conc.
    (uM)    		Volume
    (fL)    		Buffered
    DRG_2
  • Mammalian_cell_
    cycle
    Accession No. : 85
  • Delayed_
    Response_Genes
    Pathway No. : 1080
    		• 0.5200No

    DRG_2 acting as a Summed Molecule in      Mammalian_cell_cycle Network
     Accession NanePathway NameTargetInput
    1
  • Mammalian_cell_
    cycle
    Accession No. : 85
  • Early_Response_
    Genes
    Pathway No. : 1079
    		• DRG_2BDRG_2
     
    2
  • Mammalian_cell_
    cycle
    Accession No. : 85
  • Delayed_
    Response_Genes
    Pathway No. : 1080
    		• DRG_2ADRG_2
     

    DRG_2 acting as a Product in a reaction in      Mammalian_cell_cycle Network
    Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider.
    NameAccession NamePathway NameKfKbKdtauReagents
    DRG_dimerize
  • Mammalian_cell_
    cycle
    Accession No. : 85
  • Delayed_
    Response_Genes
    Pathway No. : 1080
    		• 10
    (uM^-1 s^-1)    		10
    (s^-1)    		Keq = 1(uM)-Substrate
    DRG_dup
    DRG_dup

    Product
    DRG_2


    Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
    This Copyright is applied to ensure that the contents of this database remain freely available. Please see FAQ for details.