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Name Notes Model

Molecule Parameter List for PP2A

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network. The text color of a molecule is highlighted by color.

Statistics

PP2A participated as	Molecule	Sum total of	Enzyme	Substrate of an enzyme	Product of an enzyme	Substrate in Reaction	Product in Reaction
No. of occurrences	1	0	2	0	0	0	0

Accession and Pathway Details

Accession Name	Accession No.	Accession Type	Pathway Link
AKT	87	Network	Shared_Object_AKT,  AKT_mod
This is one of the sub-model of BDNF signaling cascade. PIP3 activies AKT, leading to accumulation of Rheb-GTP, a regulator of mTOR.

PP2A acting as a Molecule in  AKT Network

Name	Accession Name	Pathway Name	Initial Conc. (uM)	Volume (fL)	Buffered
PP2A	AKT Accession No. : 87	Shared_Object_ AKT Pathway No. : 1085	0.15	999.97	No
Protein Phosphatase

PP2A acting as an Enzyme in  AKT Network

	Enzyme Molecule / Enzyme Activity	Accession Name	Pathway Name	Km (uM)	kcat (s^-1)	Ratio	Enzyme Type	Reagents
1	PP2A / Dephos_ AKTser473	AKT Accession No. : 87	Shared_Object_ AKT Pathway No. : 1085	4.8	1.8	4	explicit E-S complex	Substrate PIP3_AKT-t308_ s473 Product PIP3_AKT_thr308
2	PP2A / Dephosph_ AKTthr308	AKT Accession No. : 87	Shared_Object_ AKT Pathway No. : 1085	4.80015	1.8	4	explicit E-S complex	Substrate PIP3_AKT_thr308 Product PIP3_AKT