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Molecule Parameter List for PIP3_AKT-t308_s473

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by color.
Statistics
PIP3_AKT-t308_s473 participated asMoleculeSum total ofEnzymeSubstrate of an enzymeProduct of an enzymeSubstrate in ReactionProduct in Reaction
No. of occurrences1011100

Accession and Pathway Details
Accession NameAccession No.Accession TypePathway Link
AKT87Network
Shared_Object_AKT,  AKT_mod 
This is one of the sub-model of BDNF signaling cascade. PIP3 activies AKT, leading to accumulation of Rheb-GTP, a regulator of mTOR.

PIP3_AKT-t308_s473 acting as a Molecule in  AKT Network
NameAccession NamePathway NameInitial Conc.
(uM)		Volume
(fL)		Buffered
PIP3_AKT-t308_s473AKT
Accession No. : 87		AKT_mod
Pathway No. : 1086		0999.97No
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PIP3_AKT-t308_s473 acting as an Enzyme in  AKT Network
Enzyme Molecule /
Enzyme Activity		Accession NamePathway NameKm (uM)kcat (s^-1)RatioEnzyme TypeReagents
  • PIP3_AKT-t308_
    s473     /
    TSC2_phospho
    		• AKT
    Accession No. : 87    		AKT_mod
    Pathway No. : 1086    		10.299964explicit E-S complexSubstrate
    TSC1-TSC2

    Product
    TSC1-TSC2*

    PIP3_AKT-t308_s473 acting as a Substrate for an Enzyme in      AKT Network
    Enzyme Molecule /
    Enzyme Activity    		Accession NamePathway NameKm (uM)kcat (s^-1)RatioEnzyme TypeReagents
    PP2A  /
  • Dephos_
    AKTser473
    		• AKT
    Accession No. : 87
  • Shared_Object_
    AKT
    Pathway No. : 1085
    		• 4.81.84explicit E-S complexSubstrate
  • PIP3_AKT-t308_
    s473

    Product
    PIP3_AKT_thr308

    • PIP3_AKT-t308_s473 acting as a Product of an Enzyme in      AKT Network
    Enzyme Molecule /
    Enzyme Activity    		Accession NamePathway NameKm (uM)kcat (s^-1)RatioEnzyme TypeReagents
    PIP3_PDK2  /
    phosp_AKTser473    		AKT
    Accession No. : 87    		AKT_mod
    Pathway No. : 1086    		0.800013204explicit E-S complexSubstrate
    PIP3_AKT_thr308

    Product
  • PIP3_AKT-t308_
    s473


    • Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
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