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Molecule Parameter List for TSC1-TSC2*

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by color.
Statistics
TSC1-TSC2* participated asMoleculeSum total ofEnzymeSubstrate of an enzymeProduct of an enzymeSubstrate in ReactionProduct in Reaction
No. of occurrences1000110

Accession and Pathway Details
Accession NameAccession No.Accession TypePathway Link
AKT87Network
Shared_Object_AKT AKT_mod 
This is one of the sub-model of BDNF signaling cascade. PIP3 activies AKT, leading to accumulation of Rheb-GTP, a regulator of mTOR.

TSC1-TSC2* acting as a Molecule in  
AKT Network
NameAccession NamePathway NameInitial Conc.
(uM)
Volume
(fL)
Buffered
TSC1-TSC2*AKT
Accession No. : 87
AKT_mod
Pathway No. : 1086
0999.97No

TSC1-TSC2* acting as a Product of an Enzyme in  
AKT Network
Enzyme Molecule /
Enzyme Activity
Accession NamePathway NameKm (uM)kcat (s^-1)RatioEnzyme TypeReagents
  • PIP3_AKT-t308_
    s473
      /
    TSC2_phospho
  • AKT
    Accession No. : 87
    AKT_mod
    Pathway No. : 1086
    10.299964explicit E-S complexSubstrate
    TSC1-TSC2

    Product
    TSC1-TSC2*

    TSC1-TSC2* acting as a Substrate in a reaction in  
    AKT Network
    Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider.
    NameAccession NamePathway NameKfKbKdtauReagents
  • TSC1-2_
    dephospho
  • AKT
    Accession No. : 87
    AKT_mod
    Pathway No. : 1086
    0.01
    (s^-1)
    0
    (s^-1)
    --Substrate
    TSC1-TSC2*

    Product
    TSC1-TSC2



    Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
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