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Molecule Parameter List for CaMKIII

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by color.
Statistics
CaMKIII participated asMoleculeSum total ofEnzymeSubstrate of an enzymeProduct of an enzymeSubstrate in ReactionProduct in Reaction
No. of occurrences1002011

Accession and Pathway Details
Accession NameAccession No.Accession TypePathway Link
CaMKIII90Network
Shared_Object_CaMKIII CaM 
CaMKIII is activated by Ca2+ and inactivated by S6K. Since CaMKIII inhibits eEF2, the net effect of Ca2+ on elongation is inhibitory and of S6K is excitatory

CaMKIII acting as a Molecule in  
CaMKIII Network
NameAccession NamePathway NameInitial Conc.
(uM)
Volume
(fL)
Buffered
CaMKIIICaMKIII
Accession No. : 90
  • Shared_Object_
    CaMKIII

    Pathway No. : 1093
  • 0.061000No

    CaMKIII acting as a Substrate for an Enzyme in  
    CaMKIII Network
     Enzyme Molecule /
    Enzyme Activity
    Accession NamePathway NameKm (uM)kcat (s^-1)RatioEnzyme TypeReagents
    1S6K_thr-252  /
    camkIII_phospho
    CaMKIII
    Accession No. : 90
  • Shared_Object_
    CaMKIII

    Pathway No. : 1093
  • 114explicit E-S complexSubstrate
    CaMKIII

    Product
    CaMKIII*
    2S6K_basal  /
    CaMKIII_basal
    CaMKIII
    Accession No. : 90
  • Shared_Object_
    CaMKIII

    Pathway No. : 1093
  • 0.999896104explicit E-S complexSubstrate
    CaMKIII

    Product
    CaMKIII*

    CaMKIII acting as a Substrate in a reaction in  
    CaMKIII Network
    Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider.
    NameAccession NamePathway NameKfKbKdtauReagents
  • CaMKIII_bind_
    CaM-Ca4
  • CaMKIII
    Accession No. : 90
  • Shared_Object_
    CaMKIII

    Pathway No. : 1093
  • 99
    (uM^-1 s^-1)
    0.09
    (s^-1)
    Kd(bf) = 0.0009(uM)-Substrate
    CaM-Ca4
    CaMKIII

    Product
    CaMKIII_CaM-Ca4

    CaMKIII acting as a Product in a reaction in  
    CaMKIII Network
    Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider.
    NameAccession NamePathway NameKfKbKdtauReagents
    dephosp_CaMKIIICaMKIII
    Accession No. : 90
  • Shared_Object_
    CaMKIII

    Pathway No. : 1093
  • 0.07
    (s^-1)
    0
    (s^-1)
    --Substrate
    CaMKIII*

    Product
    CaMKIII



    Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
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