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Molecule Parameter List for CaMKIII_CaM-Ca4 | The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by  color. | | Statistics |
Accession and Pathway Details | |
| Accession Name | Accession No. | Accession Type | Pathway Link | | CaMKIII | 90 | Network |
Shared_Object_CaMKIII, CaM | | CaMKIII is activated by Ca2+ and inactivated by S6K. Since CaMKIII inhibits eEF2, the net effect of Ca2+ on elongation is inhibitory and of S6K is excitatory |
CaMKIII_CaM-Ca4 acting as a Molecule in CaMKIII Network
| Name | Accession Name | Pathway Name | Initial Conc.
(uM) | Volume
(fL) | Buffered | | CaMKIII_CaM-Ca4 | CaMKIII
Accession No. : 90 | Shared_Object_
CaMKIII
Pathway No. : 1093 | 0 | 1000 | No |
CaMKIII_CaM-Ca4 acting as an Enzyme in CaMKIII Network
Enzyme Molecule /
Enzyme Activity | Accession Name | Pathway Name | Km (uM) | kcat (s^-1) | Ratio | Enzyme Type | Reagents | CaMKIII_CaM-Ca4 /
phospho
| CaMKIII
Accession No. : 90 | Shared_Object_
CaMKIII
Pathway No. : 1093 | 1.99998 | 10 | 4 | explicit E-S complex | Substrate
eEF2
Product
eEFthr-56
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CaMKIII_CaM-Ca4 acting as a Product in a reaction in CaMKIII Network
| Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated.
Kd for higher order reaction are not consider. |
| Name | Accession Name | Pathway Name | Kf | Kb | Kd | tau | Reagents | CaMKIII_bind_
CaM-Ca4 | CaMKIII
Accession No. : 90 | Shared_Object_
CaMKIII
Pathway No. : 1093 | 99
(uM^-1 s^-1) | 0.09
(s^-1) | Kd(bf) = 0.0009(uM) | - | Substrate
CaM-Ca4
CaMKIII
Product
CaMKIII_CaM-Ca4
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| Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
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