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Reaction List for pathway Ras (Pathway Number 58) in Accession 3d_fold_model (Accession Number 8) |
Entries are grouped according to Pathway Number and they are alternately color coded using  and  color.
Further ordering can be done to the table header.   indicates that ordering is done according to ascending or descending order.Keq is calculated only for first order reactions. Kd is calculated only for second order reactions. [nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules] |
| Reaction Name | Pathway Name / Pathway No. | Kf | Kb | Kd | tau | Reagents | |
| 1 | dephosph-GEF | Ras Pathway No. 58 | 1 (s^-1) | 0 (s^-1) | - | - | Substrate: GEF* Products: inact-GEF |
| 2 | dephosph-GAP | Ras Pathway No. 58 | 0.1 (s^-1) | 0 (s^-1) | - | - | Substrate: GAP* Products: GAP | Assume a reasonably good rate for dephosphorylating it, 1/sec |
| 3 | Pase | Ras Pathway No. 58 | 0.0001 (s^-1) | 0 (s^-1) | - | - | Substrate: GTP-Ras Products: GDP-Ras | This is extremely slow (1e-4), but it is significant as so little GAP actually gets complexed with it that the total GTP turnover rises only by 2-3 X (see Gibbs et al, JBC 265(33) 20437-20422) and Eccleston et al JBC 268(36) 27012-27019 kf = 1e-4 |