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Enzyme List for pathway PLCbeta (Pathway Number 112) in Accession NonOsc_Ca_IP3metabolism (Accession Number 23) |
Entries are grouped according to Pathway Number and they are alternately color coded using  and  color.Further ordering can be done according to header.   arrow indicates that ordering is done according to ascending or descending order. |
| Enzyme Molecule / Enzyme Activity | Pathway Name / Pathway No. | Km (uM) | kcat (s^-1) | Ratio (k2/k3) | Enzyme Type | Reagents | ||
| 1 | PLC-Gq / PLC-Gq | PLCbeta Pathway No. 112 | 5 | 75 | 4 | explicit E-S complex | Substrate: PIP2 Product : DAG IP3(145) | |
| from Smrcka et al, 1991 Science 251: 804-807 | ||||||||
| 2 | PLC-Ca / PLC-Ca | PLCbeta Pathway No. 112 | 19.8408 | 10 | 4 | explicit E-S complex | Substrate: PIP2 Product : DAG IP3(145) | |
| From Sternweis et al Phil Trans R Soc Lond 1992, also matched by Homma et al. k1 = 1.5e-5, now 4.2e-6 k2 = 70/sec; now 40/sec k3 = 17.5/sec; now 10/sec Note that the wording in Sternweis et al is ambiguous re the Km. Also Smrcka et al; Science 251, 15.2.1991, pp804-807 | ||||||||
| 3 | PLC-Ca-Gq / PLCb-Ca-Gq | PLCbeta Pathway No. 112 | 4.99994 | 160 | 4 | explicit E-S complex | Substrate: PIP2 Product : DAG IP3(145) | |
| Km: Sternweis et al, Phil Trans R Soc Lond 1992 Vmax: Smrcka et al, Science 1991 | ||||||||
| 4 | PLC / PLC | PLCbeta Pathway No. 112 | 19.9994 | 2.5 | 4 | explicit E-S complex | Substrate: PIP2 Product : DAG IP3(145) | |
| Smrcka et al; Science 251, 15.2.1991, pp804-807 | ||||||||