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Accession Type:
Network
cAMP_pathway
Shared_Object_
cAMP_pathway
 Molecule
 Enzyme
PKA
AC
Gs

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Enzyme List for pathway Shared_Object_cAMP_pathway (Pathway Number 134)

 Molecule Name/
Site Name 		Km (uM) kcat (1/s)Ratio
(k2/k3)		Enzyme TypeSubstrate Product
1 Enzyme Activity:
phosph-PDE

Enzyme Molecule:
PKA-active		7.594explicit E-S complexcAMP-PDE
cAMP-PDE*
  See Bramson et al CRC crit rev Biochem 15:2 93-124. The rates there are for peptide substrates and too fast. Scaled down by a factor of 3 as per Cohen et al FEBS Lett 76:182-86 (1977).


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