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Enzyme List for pathway EGFR (Pathway Number 232)
| Molecule Name/ Site Name | Km (uM) | kcat (1/s) | Ratio (k2/k3) | Enzyme Type | Substrate | Product | |
| 1 | Enzyme Activity: phosph_Shc Enzyme Molecule: L.EGFR | 0.8333 | 0.2 | 4 | explicit E-S complex | SHC | SHC* |
| Rates from Okada et al JBC 270:35 pp 20737 1995 Km = 0.70 to 0.85 uM, Vmax = 4.4 to 5.0 pmol/min. Unfortunately the amount of enzyme is not known, the prep is only partially purified. Time course of phosph is max within 30 sec, falls back within 20 min. Ref: Sasaoka et al JBC 269:51 32621 1994. Use k3 = 0.1 based on this tau. | |||||||
| Pathway Detail | Molecule List | Enzyme List | Reaction List |