Enter a Search String |
| Special character and space not allowed in the query term. Search string should be at least 2 characters long. |
Enzyme List for pathway LacI_2nd_copy (Pathway Number 302)
| Molecule Name/ Site Name | Km (uM) | kcat (1/s) | Ratio (k2/k3) | Enzyme Type | Substrate | Product | |
| 1 | Enzyme Activity: Lac_active_ transcription Enzyme Molecule: Lac_operator_ activator_bound | 0.0006 | 20 | 4 | Classical Michaelis-Menten V = Etot.S.Kcat/Km+S | Nucleotides | lac_mRNA |
| Lac transcription from the activator bound Lac gene. kcat is taken from Garcia & Elowitz et al. (2004) PNAS 101: 10955-60 | |||||||
| 2 | Enzyme Activity: Lac_basal_ transcription Enzyme Molecule: Lac_operator | 0.0006 | 216 | 4 | Classical Michaelis-Menten V = Etot.S.Kcat/Km+S | Nucleotides | lac_mRNA |
| Basal transcription of the Lac gene. Rates from Fig 2 Garcia and Elowitz et al.(2004) PNAS 101: 10955-60 | |||||||
| 3 | Enzyme Activity: Lac_ transcription Enzyme Molecule: Lac_operator_ 1st_bound | 0.0006 | 0.0005 | 4 | Classical Michaelis-Menten V = Etot.S.Kcat/Km+S | Nucleotides | lac_mRNA |
| Transcription of the Lac gene with only one of its promoter sites activated. Rates from Box 1 Elowitz, M. et al. (2000) N Nature 403: 335-338 | |||||||
| 4 | Enzyme Activity: Lac_ transcription1 Enzyme Molecule: Lac_operator_ 2nd_bound | 0.0006 | 0.0005 | 4 | Classical Michaelis-Menten V = Etot.S.Kcat/Km+S | Nucleotides | lac_mRNA |
| Transcription of the Lac gene with both its promoter sites activated. Rates from Box 1 Elowitz, M. et al. (2000) Nature 403: 335-338 | |||||||
| 5 | Enzyme Activity: lac_translation Enzyme Molecule: lac_mRNA | 0.0006 | 0.167 | 4 | Classical Michaelis-Menten V = Etot.S.Kcat/Km+S | Amino_Acids | Lac-1 |
| Translation of the lac mRNA. Rates from Box 1 Elowitz, M. et al (2000) Nature 403: 335-338 | |||||||
| Pathway Detail | Molecule List | Enzyme List | Reaction List |