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Accession Type:
Network
RanGTPase
Shared_Object_
RanGTPase
Nucleus
Cytoplasm
 Molecule
 Enzyme
 Reaction

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Enzyme List for pathway Cytoplasm (Pathway Number 306)

 Molecule Name/
Site Name
Km (uM) kcat (1/s)Ratio
(k2/k3)
Enzyme TypeSubstrate Product
1 Enzyme Activity:
RanGAP

Enzyme Molecule:
RanGAP
0.110.84explicit E-S complexRanBP1.RanGTP
  • GDP.Ran-cytoplas
    mic

  •   RanGAP reaction on RanGTP-RanBP1 complex kcat = 10.8 /sec Km = 0.1 uM at 25oC Table 1. Gorlich D et al (2003) EMBO J 22(5):1088-1100
    2 Enzyme Activity:
    RanGAP[1]

    Enzyme Molecule:
    RanGAP
    0.69999810.64explicit E-S complex
  • GTP.Ran-cytoplas
    mic

  • GDP.Ran-cytoplas
    mic

  •   RanGAP reaction on free RanGTP kcat = 10.6 /sec Km = 0.7 uM at 25oC Table 1. Gorlich D et al (2003) EMBO J 22(5):1088-1100


    Pathway Details   Molecule List  Enzyme List   Reaction List  


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