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Enzyme List for pathway Cytoplasm (Pathway Number 306)

 Molecule Name/
Site Name 		Km (uM) kcat (1/s)Ratio
(k2/k3)		Enzyme TypeSubstrate Product
1 Enzyme Activity:
RanGAP

Enzyme Molecule:
RanGAP		0.110.84explicit E-S complexRanBP1.RanGTP
  • GDP.Ran-cytoplas
    mic
    •   RanGAP reaction on RanGTP-RanBP1 complex kcat = 10.8 /sec Km = 0.1 uM at 25oC Table 1. Gorlich D et al (2003) EMBO J 22(5):1088-1100
    2 Enzyme Activity:
    RanGAP[1]

    Enzyme Molecule:
    RanGAP    		0.710.64explicit E-S complex
  • GTP.Ran-cytoplas
    mic
  • GDP.Ran-cytoplas
    mic
    •   RanGAP reaction on free RanGTP kcat = 10.6 /sec Km = 0.7 uM at 25oC Table 1. Gorlich D et al (2003) EMBO J 22(5):1088-1100
    Pathway DetailMolecule ListEnzyme ListReaction List