  |   |        Nucleus | 
 
 
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 Enzyme List for pathway Cytoplasm (Pathway Number 306) |   | Molecule Name/  Site Name  | Km (uM) |                             kcat (1/s) | Ratio (k2/k3) | Enzyme Type | Substrate                   | Product |  
 | 1 | 
Enzyme Activity: RanGAP
  Enzyme Molecule: RanGAP | 0.1 | 10.8 | 4 | explicit E-S complex | RanBP1.RanGTP
  | GDP.Ran-cytoplas mic
  |  |   |   RanGAP reaction on RanGTP-RanBP1 complex  kcat = 10.8 /sec  Km = 0.1 uM  at 25oC Table 1.  Gorlich D et al (2003)  EMBO J 22(5):1088-1100 |  
 | 2 | 
Enzyme Activity: RanGAP[1]
  Enzyme Molecule: RanGAP | 0.699998 | 10.6 | 4 | explicit E-S complex | GTP.Ran-cytoplas mic
  | GDP.Ran-cytoplas mic
  |  |   |   RanGAP reaction on free RanGTP  kcat = 10.6 /sec  Km = 0.7 uM  at 25oC Table 1. Gorlich D et al (2003)  EMBO J 22(5):1088-1100 |  
 
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