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Parameters for MAPK_Asthagiri_enz_fb (Pathway Number 194)
Pathway Layout
Pathway Basic Parameters
| Pathway Name | MAPK_Asthagiri_enz_fb |
| Pathway Entry Number | 194 |
| Accession Number | 46 |
| Accession Name | MAPK_Asthagiri_enz_fb |
| Species | Chinese hamster (Cricetulus griseus); mammalian |
| Tissue | Ovary - CHO cell line |
| CellCompartment | Surface + cytosol |
| Related Pathways | |
| Notes | This is a complex model to examine mechanisms that govern MAPK pathway dynamics in Chinese hamster ovary (CHO) cell lines, particularly the role of enzyme targeted negative feedback mechanism in generating downstream signal adaptation. This model simulates the results as per the simulation conditions specified for figure 7B of the paper by Asthagiri AR and Lauffenburger DA. Biotechnol Prog. (2001) 17(2):227-39. However, there is some discrepancy with the outputs shown in Figure 7B. |
Statistics
26 | 11 | 7 |
Conversion format
| This pathway is part of accession 46 and is completely specified in the file acc46.g. There is no separate files for just this pathway. |
| Format | File |
| Native Format (GENESIS format) | acc46.g |
| GENESIS Format (Annotated version) | Anno_acc46.g |
| MATLAB format | acc46.m |
| SBML format | acc46.xml |
| Pathway Detail | Molecule List | Enzyme List | Reaction List |