Enter a Search String |
| Special character and space not allowed in the query term. Search string should be at least 2 characters long. |
Reaction List for pathway CDK2-CyclinA (Pathway Number 190) |
| Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reactions is not considered. |
| Name | Kf | Kb | Kd | tau | Substrate | Product | |
| 1 | Activation | 0.813 (s^-1) | 0.557 (s^-1) | Keq = 0.6851(uM) | 0.73sec | CDK2cycA | CDK2cycA* |
| Morris et al 2002 JBC 277(26): 23847--23853 kf and kb values not published kobs2 = 2.5 +- 0.1 /sec kf=0.813/sec and kb=0.557/sec used in simulation | |||||||
| 2 | Binding | 18.9999 (uM^-1 s^-1) | 25 (s^-1) | Kd(bf) = 1.3158(uM) | - | Cdk2 CyclinA | CDK2cycA |
| kf = 19/sec/uM and kb = 25/sec Morris et al (2002 june 28) J Biol Chem. 277(26):23847-53 Table 1 pp.23849. | |||||||
| Pathway Detail | Molecule List | Enzyme List | Reaction List |