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Accession information for CDK2-CyclinA_activation_pathway (Accession Number 42)

Reaction Scheme

Accession Basic Parameters

Name CDK2-CyclinA_activation_pathway
Accession Type Pathway
Transcriber Sharat J. Vayttaden, NCBS
Developer May C. Morris, Claire Gondeau, John A. Tainer, and Gilles Divita
Entry Date (YYYY-MM-DD) 2003-01-11
Species Human, Xenopus
Tissue Expressed in E.coli
Cell Compartment Cytosol
Source Morris MC. et al. J Biol Chem. (2002) 277(26):23847-53. ( peer-reviewed publication )
Methodology Qualitative
Model Implementation Exact GENESIS implementation
Model Validation Approximates original data
Notes In this version of the CDK2/Cyclin A complex activation there is discrepancy in the first curve which plots the binding reaction of CDK2 and Cyclin A expressed in E. coli. With the published rate constants the simulation does not match the published graph (Fig.1B) in Morris MC. et al. J Biol Chem. (2002) 277(26):23847-53.

Conversion formats

Native Format (GENESIS format)    acc42.g   
GENESIS Format (Annotated version)    Anno_acc42.g   
MATLAB format    acc42.m   
SBML format    acc42.xml   

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