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Reaction List for pathway Shared_Object_RanGTPase (Pathway Number 304)

Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reactions is not considered.
  Name KfKbKdtauSubstrateProduct
1 Cytoplasmic_
transfer		0.08
(s^-1)		1.3
(s^-1)		Not applicable**-GTP.Ran-nuclear
  • GTP.Ran-cytoplas
    mic
    •   Approximation to achieve Cytoplasmic transfer as per kinetics described by Gorlich D et al (2003) EMBO J 22(5):1088-1100
    2 Nucleoplasmic_
    transfer    		10000
    (s^-1)    		0.1
    (s^-1)    		Not applicable**-NTF2-GDP.Ran
  • nuclear-NTF2-GDP
    .Ran
    •   Approximation to achieve Nucleoplasmic transfer as per kinetics described by Gorlich D et al (2003) EMBO J 22(5):1088-1100
    ** This is a trasport reation between compartments of different volumes. Therefore Kd is not applicable. Please Note Kf, Kb units are in number of molecules instead of concentration.
    Pathway DetailMolecule ListEnzyme ListReaction List