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Reaction List for pathway PP1 (Pathway Number 324) | | Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reactions is not considered. |
| | Name | Kf | Kb | Kd | tau | Substrate | Product | | 1 |
dissoc-PP1-I1 | 1
(s^-1) | 0
(uM^-1 s^-1) | - | - | PP1-I1
| PP1-active
I1
| | | Let us assume that the equil in this case is very far over to the right. This is probably safe. | | 2 |
Inact-PP1 | 499.977
(uM^-1 s^-1) | 0.1
(s^-1) | Kd(bf) = 0.0002(uM) | - | I1*
PP1-active
| PP1-I1*
| | | K inhib = 1nM from Cohen Ann Rev Bioch 1989, 4 nM from Foukes et al Assume 2 nM. kf /kb = 8.333e-4 |
Pathway Details Molecule List Enzyme List Reaction List
| Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
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