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Accession Type:
Pathway
MAPK_Asthagiri_
enz_fb
MAPK_Asthagiri_
enz_fb
 Molecule
 Enzyme
 Reaction

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Parameters for MAPK_Asthagiri_enz_fb (Pathway Number 194)

Pathway Layout

Pathway Basic Parameters

Pathway NameMAPK_Asthagiri_enz_fb
Pathway Entry Number 194
Accession Number 46
Accession Name MAPK_Asthagiri_enz_fb
Species Chinese hamster (Cricetulus griseus); mammalian
Tissue Ovary - CHO cell line
CellCompartment Surface + cytosol
Related Pathways
Notes  This is a complex model to examine mechanisms that govern MAPK pathway dynamics in Chinese hamster ovary (CHO) cell lines, particularly the role of enzyme targeted negative feedback mechanism in generating downstream signal adaptation. This model simulates the results as per the simulation conditions specified for figure 7B of the paper by Asthagiri AR and Lauffenburger DA. Biotechnol Prog. (2001) 17(2):227-39.
However, there is some discrepancy with the outputs shown in Figure 7B.

Statistics

26
11
7

Conversion format

This pathway is part of accession 46 and is completely specified in the file acc46.g.
There is no separate files for just this pathway.
FormatFile
Native Format (GENESIS format)    acc46.g   
GENESIS Format (Annotated version)    Anno_acc46.g   
MATLAB format    acc46.m   
SBML format    acc46.xml   


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