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• March 2009:
  2 March:
  Seven Model from the paper "Jain P, and Bhalla, U.S. PLoS Comput Biol. 2009 Feb;5(2)." were added.
  BDNF_Receptor
  AKT
  S6K
  4EBP
  CaMKIII
  Protein_synthesis
  mTOR_pathway
  

• September 2007:
  7 September:
  Due to network upgradation and followed by UPS failure DOQCS was not reachable, we are sorry for this inconvenient.
  

• August 2007:
  20 August:
  For most of the models Matlab and SBML file are available.
  

• July 2007:
  20 July:
  SBML AND MATLAB files for the 3d_fold_model and MAPK_MKP1_oscillation model was added.
  

• June 2007:
  28 June:
  Due to some technical issue DOQCS was not reachable for sometime, we are sorry for this inconvenient.
  

• March 2007:
  20 March:
  We are performing some essential maintenance work on the server. Due to this DOQCS was not reachable for some time, this may also result in some slow performance. We are sorry for this inconvenient.
  

• January 2007:
  12 January:
  Our VSNL link was down. Due to this DOQCS was not accessible. We are sorry for this inconvenient.

• December 2006:
  22 December:
  A Mammalian_cell_cycle from Novak B,Tyson JJ. J Theor Biol. 2004 Oct 21;230(4):563-79 was added.
  
  15 December:
  Three Model from the paper "Ajay SM, Bhalla US. Eur J Neurosci. 2004 Nov;20(10):2671-80" were added.
  Ajay_Bhalla_2004_PKM_Tuning
  Ajay_Bhalla_2004_PKM_MKP3_Tuning
  Ajay_Bhalla_2004_Feedback_Tuning
  
  Six Models on ERKII signaling
  Ajay_Bhalla_2007_Bistable
  Ajay_Bhalla_2007_PKM
  Ajay_bhalla_2007_ReacDiff1_1e-12
  Ajay_Bhalla_2007_ReacDiff1_1e-13
  Ajay_Bhalla_2007_ReacDiff2
  Ajay_Bhalla_2007_ReacDiff3
  
  4 December:
  DOQCS is now SBML compliant
  For about 30 models we have released SBML files which can be downloadable from the respective Accession Details under "Conversion formats". These models are cross checked under Copasi (4.0 Build 17 RC1), CellDesginer(3.2.1) and odesolver against GENESIS result.
  

• August 2006:
  11 August :- 
  Due to power outage DOQCS was down, we are sorry for the inconvenient.
  
  10 August :- 
  Four more models from the published paper "Abu-Soud HM et al. Biochemistry. 1999 Sep 21;38(38):12446-51" where added to the Database
  L-Arginine
  HomoArginine
  NMArginine
  NOHArginine
  

• June 2006:
  Additional information like Species, CellCompartment, Tissue along with the Methodology, Model Implementation and Validation are saved in the GENESIS file. The Anno_accno#.g contains all the information and can be accessed through GENESIS by downloading the new version of kkit11. ( http://www.ncbs.res.in/~bhalla/kkit/download.html ).
  From Accession number 59, accno#.g itself will contain the additional information.

• May 2006:
  Model of Month
  RanGTPase
  RasGTPase

• Feb 2006:
  Model of Month
  Jak-Stat_Pathway
  SOCS1_knockout
  Repressilator
  Quorum_repressilator

• Jul 2005:
  Model of Month
  AMPAR_traff_model0
  AMPAR_traff_model1
  simple_AMPAR_traff_model2
  CaMKII_noPKA_model3
  CaMKII_model3
  AMPAR_CaMKII_strong_coupling
  AMPAR_CaMKII_weak_coupling

• Feb 24 2005:
  I. An addition Match Type called Model was added in Search Tool.
  II. Matlab files for the GENESIS .g file made available.
  III. In Accession List the details of Tissue, Cell compartment, Species of the model are added.

• Dec 2 2004:
  In Enzyme Table a column called Enzyme Type added to differentiate between "Explicit E-S complex" and "Classical Michaelis-Menten". For further description refer to FAQ.

• Oct 1 2004:
  The revised version of DOQCS with better search facility and a revised database structure was made publically available. With new search features like
  - Search in Name with Match field for
     . Exact word
     . Staring With
     . Anything
  - Search in Notes with Match field for
     . Anything