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Molecule Parameter List for BDNF_TrkB_clx | The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by  color. | | Statistics |
Accession and Pathway Details | |
| Accession Name | Accession No. | Accession Type | Pathway Link | | BDNF_Receptor | 86 | Network |
Shared_Object_BDNF_Receptor, TrKB_mod, PI3K_mod | | BDNF recetor signaling is one of the sub-model in BDNF signaling cascade. BDNF activates TrKB, leading to the stimulation of PI3K and formation of PIP3. |
BDNF_TrkB_clx acting as a Molecule in BDNF_Receptor Network
| Name | Accession Name | Pathway Name | Initial Conc.
(uM) | Volume
(fL) | Buffered | | BDNF_TrkB_clx | BDNF_Receptor
Accession No. : 86 | TrKB_mod
Pathway No. : 1083 | 0 | 999.97 | No |
BDNF_TrkB_clx acting as a Substrate in a reaction in BDNF_Receptor Network
| Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated.
Kd for higher order reaction are not consider. |
| Name | Accession Name | Pathway Name | Kf | Kb | Kd | tau | Reagents | | Dimeriz_TrKB | BDNF_Receptor
Accession No. : 86 | TrKB_mod
Pathway No. : 1083 | 1
(uM^-1 s^-1) | 0.02
(s^-1) | Kd(bf) = 0.02(uM) | - | Substrate
BDNF_TrkB_clx
TrKB
Product
BDNF_TrkB2_clx
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BDNF_TrkB_clx acting as a Product in a reaction in BDNF_Receptor Network
| Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated.
Kd for higher order reaction are not consider. |
| Name | Accession Name | Pathway Name | Kf | Kb | Kd | tau | Reagents | | Ligand_binding | BDNF_Receptor
Accession No. : 86 | TrKB_mod
Pathway No. : 1083 | 1.0001
(uM^-1 s^-1) | 0.05
(s^-1) | Kd(bf) = 0.05(uM) | - | Substrate
BDNF
TrKB
Product
BDNF_TrkB_clx
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| Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
This Copyright is applied to ensure that the contents of this database remain freely available. Please see FAQ for details. |
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