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Molecule Parameter List for Shc*

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by color.
Statistics
Shc* participated asMoleculeSum total ofEnzymeSubstrate of an enzymeProduct of an enzymeSubstrate in ReactionProduct in Reaction
No. of occurrences1000120

Accession and Pathway Details
Accession NameAccession No.Accession TypePathway Link
BDNF_Receptor86Network
Shared_Object_BDNF_Receptor TrKB_mod PI3K_mod 
BDNF recetor signaling is one of the sub-model in BDNF signaling cascade. BDNF activates TrKB, leading to the stimulation of PI3K and formation of PIP3.

Shc* acting as a Molecule in  
BDNF_Receptor Network
NameAccession NamePathway NameInitial Conc.
(uM)
Volume
(fL)
Buffered
Shc*BDNF_Receptor
Accession No. : 86
  • Shared_Object_
    BDNF_Receptor

    Pathway No. : 1082
  • 0999.97No

    Shc* acting as a Product of an Enzyme in  
    BDNF_Receptor Network
    Enzyme Molecule /
    Enzyme Activity
    Accession NamePathway NameKm (uM)kcat (s^-1)RatioEnzyme TypeReagents
    BDNF_TrkB2*_clx  /
    Shc_phospho
    BDNF_Receptor
    Accession No. : 86
    TrKB_mod
    Pathway No. : 1083
    0.8333060.34explicit E-S complexSubstrate
    Shc

    Product
    Shc*

    Shc* acting as a Substrate in a reaction in  
    BDNF_Receptor Network
    Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider.
     NameAccession NamePathway NameKfKbKdtauReagents
    1Shc*_dephosphoBDNF_Receptor
    Accession No. : 86
    PI3K_mod
    Pathway No. : 1084
    0.2
    (s^-1)
    0
    (s^-1)
    --Substrate
    Shc*

    Product
    Shc
    2Grb2_bind_ShcBDNF_Receptor
    Accession No. : 86
    PI3K_mod
    Pathway No. : 1084
    1
    (uM^-1 s^-1)
    1
    (s^-1)
    Kd(bf) = 1(uM)-Substrate
    Grb2
    Shc*

    Product
    Shc*_Grb2_clx



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