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Molecule Parameter List for PIP2

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by

color.

Statistics

*PIP2* participated as	Molecule	Sum total of	Enzyme	Substrate of an enzyme	Product of an enzyme	Substrate in Reaction	Product in Reaction
No. of occurrences	1	0	0	3	1	0	0

Accession and Pathway Details

Accession Name	Accession No.	Accession Type	Pathway Link
BDNF_Receptor	86	Network	Shared_Object_BDNF_Receptor, TrKB_mod, PI3K_mod
BDNF recetor signaling is one of the sub-model in BDNF signaling cascade. BDNF activates TrKB, leading to the stimulation of PI3K and formation of PIP3.

PIP2 acting as a Molecule in BDNF_Receptor Network

Name	Accession Name	Pathway Name	Initial Conc. (uM)	Volume (fL)	Buffered
PIP2	BDNF_Receptor Accession No. : 86	PI3K_mod Pathway No. : 1084	7	999.97	Yes

PIP2 acting as a Substrate for an Enzyme in BDNF_Receptor Network

	Enzyme Molecule / Enzyme Activity	Accession Name	Pathway Name	Km (uM)	kcat (s^-1)	Ratio	Enzyme Type	Reagents
1	Shc*_Grb2-Gab1_ PI3K_clx / Phospho	BDNF_Receptor Accession No. : 86	TrKB_mod Pathway No. : 1083	4.00001	4	4	explicit E-S complex	Substrate PIP2 Product PIP3
2	PI3K_basal / basal_phosp	BDNF_Receptor Accession No. : 86	PI3K_mod Pathway No. : 1084	4.00002	4	4	explicit E-S complex	Substrate PIP2 Product PIP3
3	Ras-GTP_PI3K / PIP2_phospho_ Ras-GTP	BDNF_Receptor Accession No. : 86	Shared_Object_ BDNF_Receptor Pathway No. : 1082	4.00002	4	4	explicit E-S complex	Substrate PIP2 Product PIP3

PIP2 acting as a Product of an Enzyme in BDNF_Receptor Network

Enzyme Molecule / Enzyme Activity	Accession Name	Pathway Name	Km (uM)	kcat (s^-1)	Ratio	Enzyme Type	Reagents
PTEN / PIP3_dephosp	BDNF_Receptor Accession No. : 86	Shared_Object_ BDNF_Receptor Pathway No. : 1082	0.0799995	5.5	4	explicit E-S complex	Substrate PIP3 Product PIP2

Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
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