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Molecule Parameter List for Rheb-GTP

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by color.
Statistics
Rheb-GTP participated asMoleculeSum total ofEnzymeSubstrate of an enzymeProduct of an enzymeSubstrate in ReactionProduct in Reaction
No. of occurrences1001001

Accession and Pathway Details
Accession NameAccession No.Accession TypePathway Link
AKT87Network
Shared_Object_AKT AKT_mod 
This is one of the sub-model of BDNF signaling cascade. PIP3 activies AKT, leading to accumulation of Rheb-GTP, a regulator of mTOR.

Rheb-GTP acting as a Molecule in  
AKT Network
NameAccession NamePathway NameInitial Conc.
(uM)
Volume
(fL)
Buffered
Rheb-GTPAKT
Accession No. : 87
  • Shared_Object_
    AKT

    Pathway No. : 1085
  • 1999.97No

    Rheb-GTP acting as a Substrate for an Enzyme in  
    AKT Network
    Enzyme Molecule /
    Enzyme Activity
    Accession NamePathway NameKm (uM)kcat (s^-1)RatioEnzyme TypeReagents
    TSC1-TSC2  /
    TSC2phospho
    AKT
    Accession No. : 87
  • Shared_Object_
    AKT

    Pathway No. : 1085
  • 0.299998204explicit E-S complexSubstrate
    Rheb-GTP

    Product
    Rheb-GDP

    Rheb-GTP acting as a Product in a reaction in  
    AKT Network
    Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider.
    NameAccession NamePathway NameKfKbKdtauReagents
    GDP_to_GTPAKT
    Accession No. : 87
  • Shared_Object_
    AKT

    Pathway No. : 1085
  • 0.2
    (s^-1)
    0
    (s^-1)
    --Substrate
    Rheb-GDP

    Product
    Rheb-GTP



    Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
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