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Molecule Parameter List for 40S

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by color.
Statistics
40S participated asMoleculeSum total ofEnzymeSubstrate of an enzymeProduct of an enzymeSubstrate in ReactionProduct in Reaction
No. of occurrences1000310

Accession and Pathway Details
Accession NameAccession No.Accession TypePathway Link
S6K88Network
Shared_Object_S6K mTOR_model S6Kinase 
Rheb-GTP activates TOR, and along with convergent input from MAPK, leads to S6K activation and formation of the active 40S for translation

40S acting as a Molecule in  
S6K Network
NameAccession NamePathway NameInitial Conc.
(uM)
Volume
(fL)
Buffered
40SS6K
Accession No. : 88
  • Shared_Object_
    S6K

    Pathway No. : 1087
  • 01000No
    Activated form of S6

    40S acting as a Product of an Enzyme in  
    S6K Network
     Enzyme Molecule /
    Enzyme Activity
    Accession NamePathway NameKm (uM)kcat (s^-1)RatioEnzyme TypeReagents
    1S6K_thr-412  /
    S6_phos
    S6K
    Accession No. : 88
    S6Kinase
    Pathway No. : 1089
    0.2500030.014explicit E-S complexSubstrate
    40S_inact

    Product
    40S
    2S6K_thr-252  /
    S6_phospho
    S6K
    Accession No. : 88
  • Shared_Object_
    S6K

    Pathway No. : 1087
  • 0.2500030.14explicit E-S complexSubstrate
    40S_inact

    Product
    40S
    340S_basal  /
    basal
    S6K
    Accession No. : 88
  • Shared_Object_
    S6K

    Pathway No. : 1087
  • 0.2500030.14explicit E-S complexSubstrate
    40S_inact

    Product
    40S

    40S acting as a Substrate in a reaction in  
    S6K Network
    Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider.
    NameAccession NamePathway NameKfKbKdtauReagents
    S6_dephosphS6K
    Accession No. : 88
    S6Kinase
    Pathway No. : 1089
    0.01
    (s^-1)
    0
    (s^-1)
    --Substrate
    40S

    Product
    40S_inact



    Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
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