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Result: 1 - 10 of 10 rows are displayed

Enzyme List for pathway MAPK (Pathway Number 139) in Accession MAPK_osc (Accession Number 27)

Entries are grouped according to Pathway Number and they are alternately color coded using  and   color.
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  Enzyme Molecule /

 Enzyme Activity
Pathway Name / 
Pathway No.
Km
(uM)
kcat
(s^-1)
Ratio
(k2/k3)
Enzyme TypeReagents
1 int1 /
2
MAPK

Pathway No. 139
0.0080.254Classical Michaelis-Menten
V = Etot.S.Kcat/Km+S
Substrate: 
MKKK-P
Product : 
MKKK
  Km is 8nM and Vmax is 0.25nM.s-1 from Kholodenko, 2000.
2 MKKK-P /
3
MAPK

Pathway No. 139
0.01500010.0254Classical Michaelis-Menten
V = Etot.S.Kcat/Km+S
Substrate: 
MKK
Product : 
MKK-P
  Km is 15 nM and Vmax is 0.025s-1 from Kholodenko, 2000
3 MKKK-P /
4
MAPK

Pathway No. 139
0.01500010.0254Classical Michaelis-Menten
V = Etot.S.Kcat/Km+S
Substrate: 
MKK-P
Product : 
MKK-PP
  Km is 15nM and Vmax is 0.025s-1 from Kholodenko, 2000.
4 int3 /
6
MAPK

Pathway No. 139
0.0150.754Classical Michaelis-Menten
V = Etot.S.Kcat/Km+S
Substrate: 
MKK-P
Product : 
MKK
  The Km is 15nM and the Vmax is 0.75nM.s-1 from Kholodenko 2000.
5 int5 /
10
MAPK

Pathway No. 139
0.01499970.54Classical Michaelis-Menten
V = Etot.S.Kcat/Km+S
Substrate: 
MAPK-P
Product : 
MAPK
  The Km is 15nM and Vmax is 0.5nM.s-1 from Kholodenko, 2000
6 int2 /
5
MAPK

Pathway No. 139
0.0150.754Classical Michaelis-Menten
V = Etot.S.Kcat/Km+S
Substrate: 
MKK-PP
Product : 
MKK-P
  The Km is 15nM and Vmax is 0.75nM.s-1 from Kholodenko, 2000
7 int4 /
9
MAPK

Pathway No. 139
0.01499970.54Classical Michaelis-Menten
V = Etot.S.Kcat/Km+S
Substrate: 
MAPK-PP
Product : 
MAPK-P
  The Km is 15nM and Vmax is 0.5nM.s-1 from Kholodenko, 2000
8 Ras-MKKKK /
1
MAPK

Pathway No. 139
0.012.54Classical Michaelis-Menten
V = Etot.S.Kcat/Km+S
Substrate: 
MKKK
Product : 
MKKK-P
  The Km is 10nM and Vmax is 2.5nM sec^-1. We assume that there is 1 nM of the Ras-MKKKK. From Kholodenko, 2000. If the enzymes are not flagged as Available, then this Km should be set to 0.1 to obtain oscillations.
9 MKK-PP /
7
MAPK

Pathway No. 139
0.01500010.0254Classical Michaelis-Menten
V = Etot.S.Kcat/Km+S
Substrate: 
MAPK
Product : 
MAPK-P
  The Km is 15nM which is 0.015uM Vmax is 0.025s-1 from Kholodenko, 2000.
10 MKK-PP /
8
MAPK

Pathway No. 139
0.01500010.0254Classical Michaelis-Menten
V = Etot.S.Kcat/Km+S
Substrate: 
MAPK-P
Product : 
MAPK-PP
  The Km is 15nM which is 0.015uM and Vmax is 0.025s-1 from Kholodenko, 2000

 
Result: 1 - 10 of 10 rows are displayed



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