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Molecule List for pathway PP2B (Pathway Number 83) in Accession Synaptic_Network (Accession Number 16)

Default ordering is done according to Pathway Number. Table headers can be used for changing the default ordering.
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The entries are grouped according to Pathway Number and are alternately color coded using  and  color.

BufferedSum Total Of
1 CaMCa2-CANABNetwork00No
    Ca2.CaM.Ca4.CaNAB The CaM has only 2 calciums attached, but CaNAB has all 4. This contributes equally to enzyme activity along with the Ca3 and Ca4 forms.
2 CaMCa3-CaNABNetwork00No
    Ca3.CaM.Ca4.CaNAB This is assumed to have the same enzymatic activity as the other Ca states of CaM bound to CaNAB. Hence I just put this into a summation with the other states and utilize the sum for the enzymatic steps.
3 CaMCa4-CaNABNetwork00No
    Ca4.CaM.Ca4.CaNAB. This form is fullly loaded with Ca. Its activity is assumed to be the same as the lower Ca-bound forms of CaM.Ca4.CaNAB.
4 CaNABNetwork10No
    Calcineurin A and B subunits. We assume that the A and B subunits of PP2B are always bound under physiological conditions. Tallant and Cheung '83 Biochem 22 3630-3635 have conc in many species, average for mammalian brain is around 1 uM.
5 CaNAB-Ca2Network00No
    Form of CaN with two Calciums bound.

Result: 1 - 5 of 5 rows are displayed

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