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Molecule List for pathway PP2B (Pathway Number 83) in Accession Synaptic_Network (Accession Number 16)

Default ordering is done according to Pathway Number. Table headers can be used for changing the default ordering.
arrow indicates that ordering is done according to ascending or descending order.
The entries are grouped according to Pathway Number and are alternately color coded using  and  color.
  NameAccession
Type
Initial
Conc.

(uM)
Volume
(fL)
BufferedSum Total Of
1 CaMCa2-CANABNetwork01000No
    Ca2.CaM.Ca4.CaNAB The CaM has only 2 calciums attached, but CaNAB has all 4. This contributes equally to enzyme activity along with the Ca3 and Ca4 forms.
2 CaMCa3-CaNABNetwork01000No
    Ca3.CaM.Ca4.CaNAB This is assumed to have the same enzymatic activity as the other Ca states of CaM bound to CaNAB. Hence I just put this into a summation with the other states and utilize the sum for the enzymatic steps.
3 CaMCa4-CaNABNetwork01000No
    Ca4.CaM.Ca4.CaNAB. This form is fullly loaded with Ca. Its activity is assumed to be the same as the lower Ca-bound forms of CaM.Ca4.CaNAB.
4 CaNABNetwork11000No
    Calcineurin A and B subunits. We assume that the A and B subunits of PP2B are always bound under physiological conditions. Tallant and Cheung '83 Biochem 22 3630-3635 have conc in many species, average for mammalian brain is around 1 uM.
5 CaNAB-Ca2Network01000No
    Form of CaN with two Calciums bound.

 
Result: 1 - 5 of 5 rows are displayed



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