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Accession Type:
Network
mRNA synthesis
Shared Object_
mRNA synthesis
compartment_1compartment_1
 Molecule
 Enzyme
 Reaction
compartment_2compartment_2

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Enzyme List for pathway compartment_1 (Pathway Number 1113)

 Molecule Name/
Site Name 		Km (uM) kcat (1/s)Ratio
(k2/k3)		Enzyme TypeSubstrate Product
1 Enzyme Activity:
basal_mRNA_
synthesis

Enzyme Molecule:
Basal_
transcription		1.08120.054explicit E-S complexNucleotides
mRNA_clx
 
2 Enzyme Activity:
CREBdephos

Enzyme Molecule:
PP1_active_n		514explicit E-S complexpCREB_CRE
CREB_CRE
 
3 Enzyme Activity:
CREB_phosph

Enzyme Molecule:
pCaMKIV_CaM_Ca_
nuc		5.50.74explicit E-S complexCREB_CRE
pCREB_CRE
 
4 Enzyme Activity:
I1_phospho

Enzyme Molecule:
PKA_dash_
active_n		7.594explicit E-S complexI1n
I1_star_n
 
5 Enzyme Activity:
I1_star_dephosp

Enzyme Molecule:
PP2An		7.828564explicit E-S complexI1_star_n
I1n
 
6 Enzyme Activity:
mRNA_syn

Enzyme Molecule:
Transcription_
clx		1.080.054explicit E-S complexNucleotides
mRNA_clx
 
7 Enzyme Activity:
MSK1_dash_
phospho

Enzyme Molecule:
pMSK1_n		20.14explicit E-S complexCREB_CRE
pCREB_CRE
 
8 Enzyme Activity:
MSK1_dephosp

Enzyme Molecule:
PP2An		8.799914explicit E-S complexpMSK1_n
MSK1_n
 
9 Enzyme Activity:
MSK1_phospho

Enzyme Molecule:
MAPK_star_n		5.29990.14explicit E-S complexMSK1_n
pMSK1_n
 
10 Enzyme Activity:
RSK_phsoph_CREB

Enzyme Molecule:
active_RSK2_n		50.14explicit E-S complexCREB_CRE
pCREB_CRE
 


Pathway Details   Molecule List  Enzyme List   Reaction List  

Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
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