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Molecule Parameter List for NO | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network. The text color of a molecule is highlighted by  color. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Statistics | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| NO participated as | Molecule | Sum total of | Enzyme | Substrate of an enzyme | Product of an enzyme | Substrate in Reaction | Product in Reaction |
| No. of occurrences | 1 | 0 | 0 | 0 | 0 | 0 | 1 |
Accession and Pathway Details |
| Accession Name | Accession No. | Accession Type | Pathway Link |
| NOS_Iwanaga | 11 | Pathway | NOS |
| This model is based on Iwanaga T et al. Biochemistry (1999) 38(50):16629-35.The model features the catalytic activity of neuronal Nitric Oxide Synthase expressed in Escherichia coli in a four step reaction mechanism. The rates found in the model are used directly from their paper and have been determined from experiments performed at 25 C. | |||
NO acting as a Molecule in NOS_Iwanaga Network
| Name | Accession Name | Pathway Name | Initial Conc. (uM) | Volume (fL) | Buffered | |
| NO | NOS_Iwanaga Accession No. : 11 | NOS Pathway No. : 65 | 0 | 0.0016667 | No | |
| Endogenously produced NO concentrations in the course of signal transduction processes are < 100 nM. (Varner et al., Nitric oxide in the nervous system, Academic press, London, UK, pp.191-206.) | ||||||
NO acting as a Product in a reaction in NOS_Iwanaga Network
| Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider. |
| Name | Accession Name | Pathway Name | Kf | Kb | Kd | tau | Reagents |
| k4 | NOS_Iwanaga Accession No. : 11 | NOS Pathway No. : 65 | 2.7 (s^-1) | 0 (uM^-1 s^-1) | - | - | Substrate nNOS.Cit+NO Product Cit NO |
| Rate from Biochem., 1999, 38(50), 16629-16635., from rapid quenching expts at 25 C >>>>>> 2.7 +/- 0.3 | |||||||